Sökning: "micro-array"

Visar resultat 1 - 5 av 21 avhandlingar innehållade ordet micro-array.

  1. 1. Gene expression in the dorsal root ganglion and the role of PAI-1 and amphiregulin during regeneration

    Författare :Anna Nilsson; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; Djurfysiologi; Animal physiology; DRG; micro-array; peripheral nerve regeneration; mouse;

    Sammanfattning : This thesis is concerned with two aspects of peripheral nerve injury. First the early changes in the gene expression of the dorsal root ganglion (DRG) in response to sciatic nerve injury as revealed by micro-array analysis. Second an examination of the effect of PAI-1 and amphiregulin on survival and axonal outgrowth from DRG. LÄS MER

  3. 2. Molecular characterization of neuroblastoma tumors - a basis for personalized medicine

    Författare :Hanna Kryh; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroblastoma; Cancer; Tumor; SNP-array; Micro array; DNA copy number;

    Sammanfattning : Neuroblastoma is a very heterogeneous tumor, with a clinical course ranging from spontaneous regression to aggressive tumor growth. A proper stratification of the patients into different risk groups is therefore important in order to provide the most suitable treatment for each patient. LÄS MER

  4. 3. Towards a Translational Pain Model - Techniques and developments

    Författare :Leila Etemadi; Neuronano Research Center (NRC); []
    Nyckelord :UVB irradiation; Pain; Neuropeptides; Inflammation; Contralateral; Lateral spinal nucleus; Micro-array electrodes; Pan-neuronal markers; immunohistochemistry;

    Sammanfattning : Pain is a major health issue for each affected individual and has a large impact on health costs. Most of our knowledge about this defensive system rely on data from different animal experiments. There is an obvious need for a translational pain model allowing comparisons between experimental animals and humans. LÄS MER

  5. 4. Prognostic markers in prostate cancer : studies of a watchful waiting cohort with long follow up

    Författare :Andreas Josefsson; Anders Bergh; Pernilla Wikström; Pär Stattin; Anders Bjartell; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; Immunohistochemistry; Prognostic markers; biomarkers; Survival analysis; human; pathology; watchful waiting; tissue micro array; Endoglin; von willebrandt factor; ki67; ki-67; hyaluronan; patologi; Pathology;

    Sammanfattning : Background: Prostate Cancer (PC) is a common and highly variable disease. Using current diagnostic methods, the prostate specific antigen (PSA) blood test and histological grading of prostate tissue needle biopsies, it is often difficult to evaluate whether the patient has a PC that requires active treatment or not. LÄS MER

  7. 5. Role of Wnt5a in Prostate Cancer

    Författare :Azharuddin Sajid Syed Khaja; Malmö Urologisk cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate Cancer; Wnt5a; tissue micro array; Biochemical recurrence; Gene fusions;

    Sammanfattning : Wnt5a is a non-canonical secreted glycoprotein of the Wnt family that plays important roles in organ development and tissue orientation. Previous studies have reported that Wnt5a was upregulated at both mRNA and protein levels in prostate cancer, but information regarding its role in predicting clinical outcome in patients after radical prostatectomy is limited. LÄS MER