Sökning: "micro-array"
Visar resultat 6 - 10 av 21 avhandlingar innehållade ordet micro-array.
6. Prognostic molecular markers of childhood leukemia
Sammanfattning : During the last decades there has been a dramatic increase in survival rates for childhood leukemia, resulting today in an overall survival close to 90 % for children with acute lymphoblastic leukemia (ALL). This accomplishment is largely due to treatment protocols based on careful risk group assessment guiding the type and intensity of the anti-leukemic treatment. LÄS MER
7. Autism spectrum disorders : genetic and neurodevelopmental aspects in children with early diagnosis
Sammanfattning : The overall aim of the thesis was to describe the broad variability in neurodevelopmental profiles in preschool children with autism spectrum disorders (ASD) and to relate these findings to co-existing genetic conditions and other medical disorders. Children in the study were assessed with regard to neurodevelopmental characteristics, before and after intervention, and were recommended genetic testing including chromosomal micro-array. LÄS MER
8. Neural Stem and Progenitor Cells : Cellular Responses to Known and Novel Factors
Sammanfattning : Neural stem cell self-renewal and differentiation are tightly regulated events during CNS development, leading to cell division into new neural stem cells or the formation of neurons and glial cells. This thesis focuses on the cellular responses induced by known and novel factors in neural stem and progenitor cells (NSPCs). LÄS MER
9. Biomarkers in non-small cell lung carcinoma : methodological aspects and influence of gender, histology and smoking habits on estrogen receptor and epidermal growth factor family receptor signalling
Sammanfattning : Non-small cell lung carcinoma is a leading cause of cancer mortality worldwide. There are gender and smoking associated differences both in tumour types and clinical outcome. Squamous cell carcinomas (SCC) are more frequent among smoking men while females develop adenocarcinomas (ADCA). LÄS MER
10. Human Dermal Fibroblasts in Tissue Engineering
Sammanfattning : The loss or failure of tissues and/or organs is one of the most frequent problems in modern healthcare. The field of tissue engineering applies the principles of biology and engineering in order to develop functional substitutes for damaged tissues. LÄS MER