Sökning: "long-term-maintenance"

Visar resultat 16 - 20 av 22 avhandlingar innehållade ordet long-term-maintenance.

1. 16. Dysfunction in the nigrostriatal system : effects of L-DOPA and GDNF

   Författare :Nina Nevalainen; Ingrid Strömberg; Nancy Zahniser; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson’s disease; L-DOPA; dyskinesia; GDNF; dopamine; glutamate; serotonin; medicinsk utvecklings- och neurobiologi; Developmental Neurosciences;

   Sammanfattning : Parkinson’s disease is a common neurodegenerative disorder caused by nigrostriatal dopamine loss, with motor deficiencies as the primary outcome. To increase the striatal dopamine content, patients are treated with 3,4-dihydroxyphenyl-l-alanine (l-DOPA). LÄS MER

3. 17. Post-traumatic Stress Disorder – Assessment of current diagnostic definitions

   Författare :Kristina Bondjers; Filip Arnberg; Mimmie Willebrand; Mark Shevlin; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PTSD; Complex PTSD; Post-traumatic Stress; Psychological assessment; DSM-5; ICD-11; Confirmatory factor analysis; Latent class analysis; Structural equation modelling; psychometric; psychiatric diagnoses; Psychiatry; Psykiatri;

   Sammanfattning : Post-traumatic stress disorder (PTSD) is a debilitating condition that may arise after exposure to shocking, frightening, or dangerous events. Hallmark symptoms are re-experiencing, avoidance, and hyperarousal. Other common symptoms are more ancillary and overlap with other psychiatric disorders (e.g. LÄS MER

4. 18. Composition and maintenance of skin resident T-cells in health and disease

   Författare :Elena Hoffer; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Tissue-resident memory T cells (TRM) reside in healthy skin at sites of previous infections. Upon re-infection, TRM cells rapidly respond by initiating tissue inflammation and exert effector functions to eliminate pathogens. TRM cells are potent effector cells and as such, they are key players in focal inflammatory skin diseases. LÄS MER

5. 19. Pathways linking sleep, neuroimmune signaling and pain: an integrative approach

   Författare :Martin Flores Bjurström; Anestesiologi och intensivvård; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pain; neuroinflammation; inflammation; glia; central sensitization; cerebrospinal fluid; osteoarthritis; chronic postsurgical pain; groin hernia repair; sleep; sleep disturbance; perioperative; neurophysiology;

   Sammanfattning : Background and objectives: Neuroinflammation is implicated in the development and maintenance of persistent pain states, but there is limited data linking cerebrospinal fluid (CSF) inflammatory mediators with neurophysiological pain processes in humans. Study I aimed to investigate whether there are coherent changes in CSF inflammation associated with central sensitization (CS), and to evaluate potential differences in CSF levels of inflammatory mediators between osteoarthritis (OA) patients with disabling pain and pain-free controls. LÄS MER

7. 20. Beyond treatment? : widening the approach to alcohol problems and solutions

   Författare :Jan Blomqvist; Douglas Cameron; Stockholms universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Social work; Socialt arbete; Social Work; socialt arbete;

   Sammanfattning : The dissertation includes four different studies which, from different points of departure, aim to illuminate problems and prospects of social work with alcohol problems in contemporary Sweden.Paper 1 analyses the historical succession of predominant public images of, and societal responses to, alcohol problems in Sweden during the past century. LÄS MER