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Visar resultat 1 - 5 av 25 avhandlingar som matchar ovanstående sökkriterier.
1. Human leukocyte antigens with special reference to association and linkage in multiple sclerosis
Sammanfattning : The polymorphism of HLA (human leukocyte antigen) is extensive. Allelic variation has previously been detected by cellular and serological methods. Today a variety of genomic typing techniques have been developed, which give higher resolution and a possibility to detect single nucleotide variations. LÄS MER
2. Genetic studies of schizophrenia
Sammanfattning : The prevalence of schizophrenia is about 1% throughout the world. The disease is characterized by symptoms such as hallucinations, delusions and bizarre behavior. A genetic contribution to the disease was previously shown through epidemiological studies. The mitochondrial DNA was sequenced in four schizophrenic patients. LÄS MER
3. The genetics of systemic lupus erythematosus : Mapping of susceptibility loci for human SLE
Sammanfattning : Systemic lupus erythematosus (SLE) is a systemic autoimmune disease affecting organs such as skin, jointsand kidneys. Characteristic for the disease is increased production of autoantibodies, in particular against dsDNA. Previous studies of SLE in mouse models and in humans indicate polygenic inheritance and genetic heterogeneity. LÄS MER
4. Genetic studies of stroke in Northern Sweden
Sammanfattning : Stroke is a common disorder of later life with a complex etiology, including both environmental and genetic risk factors. The inherited predisposition is challenging to study due to the complexity of the stroke phenotype. LÄS MER
5. Molecular genetics of type 2 diabetes
Sammanfattning : Type 2 diabetes is a common and chronic disease caused by interactions between genetic and environmental factors. The Goto-Kakizaki (GK) rat is a well-established genetic model of type 2 diabetes. LÄS MER