Sökning: "kinin receptors"
Visar resultat 1 - 5 av 6 avhandlingar innehållade orden kinin receptors.
1. Kinin System Activation in Vasculitis
Sammanfattning : The kinin system is activated when high-molecular-weight kininogen (HK) is cleaved by plasma kallikrein thus generating bradykinin. Bradykinin is a potent proinflammatory peptide that induces plasma leakage, blood pressure drop, liberation of inflammatory cytokines and pain. LÄS MER
2. Inflammation, kinins, and kinin receptors
Sammanfattning : Evidence is accumulating that the pathogenesis of many diseases is triggered by inappropriate inflammatory responses. These serious complications may occur when the tightly regulated inflammatory network is out of balance and it is now clear that this can eventually cause substantial harm to own cells and tissues. LÄS MER
3. Kinins : important regulators in inflammation induced bone resorption
Sammanfattning : Inflammatory processes in, or in close vicinity of, the skeleton often lead to loss of bone tissue. Different cytokines have been shown to be involved as stimulators of inflammatory induced osteoclastic bone resorption. LÄS MER
4. G protein-coupled receptor regulation: The role of protein interactions and receptor trafficking
Sammanfattning : The superfamily of G protein-coupled receptors (GPCR) is the largest gene family in the human genome. GPCR-mediated signaling operates in every human cell, and about 50% of existing clinically useful drugs act through GPCR. LÄS MER
5. Nicotine and endotoxin in airway hyperreactivity and inflammation
Sammanfattning : Active, as well as passive cigarette smoke exposure is detrimental to the human health, negatively affecting the cardiovascular, respiratory and immune systems. In addition, it is also carcinogenic. LÄS MER
