Sökning: "anti-neutrophil-cytoplasmic antibodies"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden anti-neutrophil-cytoplasmic antibodies.

1. 1. Diagnostic and prognostic aspects of anti-neutrophil cytoplasmic antibodies in systemic vasculitis

   Författare :Daina Selga; Njurmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Immunologi; serologi; serology; epitope; Wegener s granulomatosis; microscopic polyangiitis; polyarteritis nodosa; capture ELISA; Immunology; anti-neutrophil cytoplasmic antibody; proteinase 3; vasculitis; nephrology; Urologi; nefrologi; Urology;

   Sammanfattning : Primary systemic vasculitis is associated with a high mortality if left untreated and it is essential to make the diagnosis before permanent organ damage has occurred. In this thesis the diagnostic and prognostic significance of anti-neutrophil cytoplasmic antibodies (ANCA) in systemic vasculitis is investigated. LÄS MER

3. 2. Kinin System Activation in Vasculitis

   Författare :Robin Kahn; Lund Pediatrik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; kinin receptors; inflammation; vasculitis; proteinase 3; neutophils; anti-neutrophil-cytoplasmic antibodies; Kinin;

   Sammanfattning : The kinin system is activated when high-molecular-weight kininogen (HK) is cleaved by plasma kallikrein thus generating bradykinin. Bradykinin is a potent proinflammatory peptide that induces plasma leakage, blood pressure drop, liberation of inflammatory cytokines and pain. LÄS MER

4. 3. The Importance of Demographic and Geographical Factors on the Incidence and Outcome of Systemic Small Vessel Vasculitis Associated with Anti-Neutrophil Cytoplasmic Antibodies

   Författare :Maria Weiner; Mårten Segelmark; Per Eriksson; Øyvind Palm; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : The anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) comprise microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA) and eosinophilic granulomatosis with polyangiitis (EGPA). Two serotypes are recognized: myeloperoxidase (MPO)-ANCA and proteinase 3 (PR3)-ANCA. LÄS MER

5. 4. Autoimmunity in glomerulonephritis; serological diagnosis and clinical outcome with special reference to Wegener´s granulomatosis and microscopic polyangiitis

   Författare :Kerstin Westman; Njurmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Wegener´s granulomatosis; vasculitis; thyroid peroxidase antibodies; proteinase 3; myeloperoxidase; antineutrophil cytoplasmic antibodies; ANCA; thyroiditis; autoantibodies; glomerulonephritis; microscopic polyangiitis; Urology; nephrology; Urologi; nefrologi;

   Sammanfattning : Autoantibodies of different specificites have been described in association with glomerulonephritis and therefore the aim of this thesis was to improve our knowledge of the different manifestations of autoimmune phenomena which are involved in the glomerulonephritides. Special reference is made to Wegener´s granulomatosis (WG) and microscopic polyangiitis (MP) which are frequently associated with the prevalence of anti-neutrophil cytoplasmic antibodies (ANCA). LÄS MER

7. 5. The role of granulocyte antibodies in monocyte and granulocyte activation

   Författare :Agneta Wikman; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :ANCA; adhesion molecules; CD11b; CD62L; granulocyte antibodies; granulocytes; monocytes; systemic vasculitis;

   Sammanfattning : Granulocytes and monocytes are important cells during the first phase of inflammation. They are activated and recruited from the blood vessels to inflammatory sites via the regulation of receptors involved in adhesion to endothelium. LÄS MER