Sökning: "ionophore"

Visar resultat 6 - 10 av 30 avhandlingar innehållade ordet ionophore.

1. 6. Studies of prostaglandin E2 formationin human monocytes

   Författare :Sofia Karlsson; Jonny Wijkander; Christina Gustafson-Svärd; Karlstads universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostaglandin E2; arachidonic acid; phospholipase A2; cyclooxygenase; prostaglandin E synthase; human monocytes; Medical cell biology; Medicinsk cellbiologi; Biomedical Sciences; Biomedicinsk vetenskap;

   Sammanfattning : Prostaglandin (PG) E2 is an eicosanoid derived from the polyunsaturated twenty carbon fatty acid arachidonic acid (AA). PGE2 has physiological as well as pathophysiological functions and is known to be a key mediator of inflammatory responses. LÄS MER

3. 7. Synthesising Metal Oxide Materials and Their Composite Nanostructures for Sensing and Optoelectronic Device Applications

   Författare :Kimleang Khun; Magnus Willander; Omer Nour; Christos Tsamis; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Hydrothermal method; metal oxide nanostructure; composite seed solution; wellaligned ZnO nanorods; composite structures; glucose and dopamine non-enzymatic sensors; heavy metals; supramolecular; UV photodetector sensor;

   Sammanfattning : Research on nanomaterials has been revolutionized in the last few years because of the attractive properties they have in comparison to the bulk phase of similar materials. These properties are physical, chemical, catalytic and optical. LÄS MER

4. 8. Expression and regulation of MMP-1 and MMP-3 in human gingival fibroblasts

   Författare :Helena Domeij; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Matrix metalloproteinases; tissue inhibitor of metalloproteinases; gingival fibroblasts; monocytes; periodontal diseases;

   Sammanfattning : Matrix metalloproteinases (MMPs) are a group of proteolytic enzymes collectively responsible for the metabolism of extra cellular matrix components. Disturbance of the physiological balance between MMPs and their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs), is implicated in several inflammatory diseases characterized by tissue degradation. LÄS MER

5. 9. Calcium channel activity and force regulation in smooth muscle: Effects of polyamines and growth stimulation

   Författare :Maria Gomez; Kardiovaskulär forskning - immunitet och ateroskleros; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; verapamil; tissue culture; portal vein; patch-clamp; calcium; spermidine; spermine; polyamines; excitation-contraction; smooth muscle; calcium channel; ionomycin.; Physiology; Fysiologi;

   Sammanfattning : The initial signal for contraction in smooth muscle is an increase in [Ca2+]i. Ca2+ ions can either enter the cytosol from the extracellular medium or be released from intracellular stores. Voltage-operated Ca2+ channels (VOC) play a dominant role in the activation of smooth muscle contraction. LÄS MER

7. 10. Biosynthesis of leukotriene B4 in hematological malignancies

   Författare :Gudmundur Runarsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :LTB 4; 5-LO; cPLA 2; iPLA 2; AML; B-ALL; B-CLL;

   Sammanfattning : Leukotrienes (LT) are biologically active metabolites of the fatty acid arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA 2), this fatty acid can be converted to leukotrienes, lipoxins, prostaglandins or thromboxane. The conversion of AA to LTA 4 is catalyzed by five-lipoxygenase (5-LO). LÄS MER