Sökning: "human microbiome"

Visar resultat 1 - 5 av 25 avhandlingar innehållade orden human microbiome.

  1. 1. Development of advanced chemical biology tools for microbiome metabolism : Chemoselective probes for enhanced metabolomics analysis

    Författare :Weifeng Lin; Daniel Globisch; Frank Schroeder; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chemical biology; Chemoselective modification; Chemical metabolomics; Bioorganic; Microbiome metabolism; Kemi; Chemistry;

    Sammanfattning : The human microbiome has a profound impact on host physiology by generating highly reactive compounds that can contribute to the development of diseases. These microbial metabolites have a substantial potential that can serve as valuable indicators or biomarkers for different health conditions. LÄS MER

  3. 2. Ultrasound and molecular biomarkers for prediction of preterm delivery in different risk groups of singleton pregnancies

    Författare :Tove Wikström; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cervical length measurement; preterm birth; ; second trimester; screening; cost-effectiveness analyzes; progesterone; human microbiome; ; transcriptome; gene expression profiles; microRNA;

    Sammanfattning : Ultrasound and molecular biomarkers for prediction of preterm delivery in women with a singleton pregnancy Tove Wikström Department of Obstetrics and Gynecology, Institute of Clinical Sciences Sahlgrenska Academy, University of Gothenburg Gothenburg, Sweden Background: Preterm delivery (PTD) is the leading cause of death in children under five years of age. Spontaneous PTD (sPTD) might be partly preventable by treating asymptomatic women having a short cervical length (CL) with vaginal progesterone. LÄS MER

  4. 3. Exploration of bacteria associated with Anopheles mosquitoes around the world : For the prevention of transmission of malaria

    Författare :Louise K. J. Nilsson; Olle Terenius; Staffan Svärd; Sebastian Håkansson; Michael Strand; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; microbiota; microbiome; vector-borne disease; 16S rRNA gene; amplicon sequencing; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Sammanfattning : Every year, hundreds of thousands of people die from malaria. Malaria is a disease caused by parasites, which are spread by female vector mosquitoes of the genus Anopheles. Current control measures against malaria are based on drugs against the parasites and vector control using insecticides. LÄS MER

  5. 4. Metabolic Modeling of the Gut Microbiome-Host Interactions and Meta’omics Integration

    Författare :Saeed Shoaie; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; meta’omics; complexity; obesity; network topology; Gut microbiome; genome-scale metabolic model; gene richness; CASINO; systems biology; flux balance analysis; diabetes;

    Sammanfattning : A large number of microbes with different strain types occupy the human gut. These gut inhabitant microbes have key roles in decomposition of indigestible dietary macronutrients before they are metabolised by the host. LÄS MER

  7. 5. Heterogeneity of human metabolism in health and disease: a modelling perspective

    Författare :Pouyan Ghaffari Nouran; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer metabolism; fatty acid metabolism; genome-scale metabolic models; community modeling; heterogeneity; lung cancer; amino acids metabolism; gut microbiome;

    Sammanfattning : Metabolism is broadly defined as the sum of biochemical reactions within cells that are involved in maintaining the living state of the organism. Profound importance of metabolism comes from the fact that it is the sole source of energy that allows life to resist to be degraded into entropy. LÄS MER