Sökning: "Bioorganic"

Visar resultat 1 - 5 av 32 avhandlingar innehållade ordet Bioorganic.

  1. 1. Development of advanced chemical biology tools for microbiome metabolism : Chemoselective probes for enhanced metabolomics analysis

    Författare :Weifeng Lin; Daniel Globisch; Frank Schroeder; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chemical biology; Chemoselective modification; Chemical metabolomics; Bioorganic; Microbiome metabolism; Kemi; Chemistry;

    Sammanfattning : The human microbiome has a profound impact on host physiology by generating highly reactive compounds that can contribute to the development of diseases. These microbial metabolites have a substantial potential that can serve as valuable indicators or biomarkers for different health conditions. LÄS MER

  3. 2. Sputtering of fullerenes and bioorganic molecules

    Författare :Gunnar Brinkmalm; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  4. 3. Conformationally Constrained Nucleic Acids as Potential RNA Targeting Therapeutics

    Författare :Zhou Chuanzheng; Jyoti Chattopadhyaya; Serge Beaucage; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bioorganic chemistry; Bioorganisk kemi; Chemistry with specialization in Bioorganic Chemistry; Kemi med inriktning mot bioorganisk kemi;

    Sammanfattning : .... LÄS MER

  5. 4. A Chemical Approach Toward the Therapeutic Optimization of Cytotoxic Bioconjugates

    Författare :Rafael Hartmann; Luke R. Odell; Fredrik Lehmann; Mats Larhed; Dario Neri; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemotherapy; antibody-drug conjugates; organic synthesis; bioorganic chemistry; synthetic method development; analytical method development; Chemistry with specialization in Bioorganic Chemistry; Kemi med inriktning mot bioorganisk kemi; Medicinal Chemistry; Läkemedelskemi; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi;

    Sammanfattning : The delivery of cytotoxicity to specific cells was recognized to be the key to the effective, chemical treatment of infectious and neoplastic diseases well over a century ago. In the context of oncology, the primary therapeutic challenge is the distinction between healthy and pathological cells despite their pronounced pheno- and genotypic similarity. LÄS MER

  7. 5. The sweet side of molecular structure : NMR spectroscopic studies of glycans and their interactions with proteins

    Författare :Christoffer Hamark; Göran Widmalm; Mario Schubert; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bioorganic chemistry; glycans; ligand-based NMR; molecular simulations; protein-carbohydrate interactions; lectins; carbohydrate conformations; 77Se NMR; structure-reactivity relationships; super-armed donors; organisk kemi; Organic Chemistry;

    Sammanfattning : In this thesis, within the topic of bioorganic chemistry, the molecular structure of carbohydrates has been studied. Carbohydrates, or glycans, are ubiquitous biomolecules exhibiting a wide range of biological roles. LÄS MER