Sökning: "homologous recombination"

Visar resultat 41 - 45 av 90 avhandlingar innehållade orden homologous recombination.

  1. 41. The function of Smc5/6 in Drosophila development and at the heterochromatin-like locus HMR in budding yeast

    Författare :Martin Tran; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The structural maintenance of chromosome 5/6 (Smc5/6) complex is one out of many factors in the cell that maintain genome stability. Smc5/6 has been implicated in processes such as DNA double-strand break (DSB) repair, replication progression, and chromosome segregation. LÄS MER

  3. 42. Nanofluidics for Static and Dynamic DNA-Protein Interaction Studies - Repair of Double-Strand Breaks from a Single-Molecule Perspective

    Författare :Robin Öz; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Single-molecule; Protein; NHEJ; Dynamic; DNA repair; HR; Biomolecule interactions; Microscopy; Fluorescence; Nanofluidics;

    Sammanfattning : Double-strand breaks (DSBs) is one of the most lethal forms of DNA damage. A single DSB may result in stalling of vital cellular machineries, and thus, requires immediate measures by the cell. LÄS MER

  4. 43. A Unified Multitude : Experimental Studies of Bacterial Chromosome Organization

    Författare :Eva Garmendia; Diarmaid Hughes; Linus Sandegren; John R. Roth; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; bacterial evolution; chromosome organization and structure; chromosomal inversions; EF-Tu; horizontal gene transfer; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Sammanfattning : Bacteria are many, old and varied; different bacterial species have been evolving for millions of years and show many disparate life-styles and types of metabolism. Nevertheless, some of the characteristics regarding how bacteria organize their chromosomes are relatively conserved, suggesting that they might be both ancient and important, and that selective pressures inhibit their modification. LÄS MER

  5. 44. Genome Evolution and Niche Differentiation of Bacterial Endosymbionts

    Författare :Kirsten Maren Ellegaard; Siv Andersson; Andrés Moya; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; niche; habitat; endosymbiont; gut microbiome; honey bee; Wolbachia; comparative; genomics;

    Sammanfattning : Most animals contain chronic microbial infections that inflict no harm on their hosts. Recently, the gut microflora of humans and other animals have been characterized. However, little is known about the forces that shape the diversity of these bacterial communities. LÄS MER

  7. 45. The Evolution of Sex Chromosomes and Dosage Compensation in Structurally Dynamic Butterfly Genomes

    Författare :Lars Höök; Niclas Backström; Elina Immonen; Beatriz Vicoso; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Sex chromosome evolution; Dosage compensation; Sex-biased gene expression; Faster-Z; Lepidoptera; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : Dimorphic sex chromosomes have evolved independently throughout evolution from initially homologous autosomes. Recombination suppression between the sex chromosomes causes one sex chromosome to degenerate, which will influence evolution of sex-linked genes. LÄS MER