Sökning: "growth restriction"

Visar resultat 6 - 10 av 111 avhandlingar innehållade orden growth restriction.

  1. 6. Growth factors and vasoactive substances in intrauterine growth restriction and preeclampsia

    Författare :Eva Östlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cordocentesis; IUGR; preeclampsia; prediction; IGF-I; IGFBP- 1; TGF-beta 1; blood gases; hypoxia; vasoconstriction; endothelin; erythropoietin; fibronectin; placenta.;

    Sammanfattning : Fetal growth restriction (FGR) is, next to prematurity, the second leading cause of perinatal morbidity and mortality. To reduce perinatal morbidity and mortality it is important to identify such fetuses in utero in order to monitor their development, and to determine the most optimal time for delivery. LÄS MER

  3. 7. Development in children born very preterm after intrauterine growth restriction with abnormal fetal blood flow

    Författare :Eva Morsing; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; umbilical artery; cognitive development; lung function; cardiovascular function; very preterm infants; Doppler ultrasound; Intrauterine growth restriction;

    Sammanfattning : Delivery of fetuses with intrauterine growth restriction (IUGR) with abnormal umbilical artery blood flow in the second trimester represents a clinical dilemma. So far, no evidence based management protocols are available adressing when to deliver these fetuses. LÄS MER

  4. 8. Brain-sparing Circulation in Growth-restricted Human Fetuses

    Författare :Jing Fu; Urogynekologi och reproduktionsfarmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics; gynaecology; andrology; reproduction; sexuality; Fetal growth-restriction.; Brain-sparing.; Oxytocin challenge test.; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet;

    Sammanfattning : The aim of the studies was to explore fetal circulatory changes relative to development of brain-sparing flow (BSF) in growth-restricted fetuses exposed to acute hypoxic stress, as provoked by uterine contractions during an oxytocin challenge test (OCT).(1) In fetuses with a normal cerebral circulation during basal conditions, signs of an acute hyperperfusion in both the arterial and venous cerebral vascular systems were demonstrated in response to acute hypoxic stress; (2) Fetuses with an already established BSF showed no further ability of brain-sparing during acute hypoxic stress; (3) In venous cerebral vessels of fetuses with established BSF, the flow responses to hypoxic stress were equivocal, indicating different reactions in areas drained by different veins, or a deranged physiological vascular response; (4) Blood flow changes occurred synchronized in the middle and anterior cerebral arteries when fetuses with an intact cerebral circulation were exposed to hypoxic stress; (5) When fetuses with an established BSF showed no further changes in the middle cerebral artery, no changes were found in the anterior cerebral artery either. LÄS MER

  5. 9. Transport of sodium and protons in the human placenta. Mechanisms in normal pregnancy and alterations in intrauterine growth restriction

    Författare :Martin Johansson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; placenta; Na K ATPase; Na H exchanger; H K ATPase; intrauterine growth restriction; BeWo cells; epithelial transport;

    Sammanfattning : The syncytiotrophoblast cell of the human placenta represents the interface between maternal and fetal blood supplies. This polarized epithelium consists of a maternal facing microvillous membrane (MVM) opposing a fetal facing basal membrane (BM). This unique syncytial cell is responsible for transfer of all nutrients to the developing fetus. LÄS MER

  7. 10. Born Small for Gestational Age : Beyond Size at Birth

    Författare :Linda Lindström; Anna-Karin Wikström; Eva Bergman; Maria Lundgren; Kjell Å Salvesen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Small for Gestational Age; SGA; Epidemiology; Pregnancy; Postnatal growth; Intrauterine growth restriction; Chronic hypertension; School performance; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : Children born small for gestational age (SGA) run increased risk of perinatal morbidity and mortality, but also of long-term health impairment. Risks on long term may vary depending on postnatal growth patterns. LÄS MER