Sökning: "functional association"

Visar resultat 11 - 15 av 505 avhandlingar innehållade orden functional association.

  1. 11. Functional properties of galectin-3. Beyond the sugar binding

    Författare :Adriana Lepur; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; galectin-3; galectin-1; M1 macrophage; M2 macrophage; self-association; fluorescence anisotropy; citrus pectin; galactomannane;

    Sammanfattning : Contemporary diseases like diabetes, asthma, atherosclerosis etc. are marked by chronic inflammation, often supported by the activity of different macrophages. Proteins from galectin family were found to contribute to disease pathophysiology. Therefore, there is an intensive interest in understanding different galectin functions. LÄS MER

  3. 12. THE ANDROGEN RECEPTOR GGN POLYMORPHISM. Genetic and functional analyses

    Författare :Kristina Lundin; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; Functional domain; Genetic predisposition; Reproductive function; Sex hormone; Transactivation function; Repeat; Polymorphism; Androgen receptor; Transcription factor; Medicin människa och djur ; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : Male sex development and reproductive function is regulated by androgens acting via the androgen receptor (AR). The AR harbours two polymorphic repeats of CAG and GGN triplets, encoding glutamines and glycines, respectively. LÄS MER

  4. 13. Functional Role of Genetic Polymorphisms Associated with Systemic Lupus Erythematosus

    Författare :Sara E Löfgren; Ulf Gyllensten; Jan Hillert; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoimmunity; systemic lupus erythematosus; genetic association; single nucleotide polymorphism; IRF5; CD226; miR-146a; Medical Science; Medicinsk vetenskap; Medical Genetics; Medicinsk genetik;

    Sammanfattning : Systemic lupus erythematosus (SLE) is a chronic and complex autoimmune disorder characterized by a failure in the mechanism of self-tolerance and production of autoantibodies, potentially affecting any organ in the body. The genetic factors behind the disease have been extensively studied in the past years and to date a list of more than 30 loci have been associated with SLE. LÄS MER

  5. 14. Functional and Nutritional Assessments in Geriatric Rehabilitation. A Feasibility Study

    Författare :Ingrid Poulsen; Institutionen för hälsovetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gerontologi; Gerontology; Feasibility; Geriatric rehabilitation; Functional status; Undernutrition; Effectiveness;

    Sammanfattning : The aim was to evaluate the effectiveness and feasibility of functional and nutritional assessments in geriatric rehabilitation in Copenhagen, Denmark, and in addition to study clinically identifiable risk factors for undernutrition, association between nutritional and ADL status, feasibility and effectiveness of nutritional intervention conducted by the nursing staff, and the nursing staffs attitudes towards nutrition-related assessments. Two data collections were conducted in the geriatric clinics in Copenhagen. LÄS MER

  7. 15. Functional genomics studies of PINK1

    Författare :Camilla Scheele; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Functional genomics has become an important and established research discipline during the last 10 years, mainly as a consequence of the completion of large-scale genome sequencing projects. The human genome is now predicted to transcribe 20,000-25,000 protein coding genes, which is only a quarter of the number suggested a few years ago. LÄS MER