Sökning: "fret"

Visar resultat 21 - 25 av 75 avhandlingar innehållade ordet fret.

  1. 21. Probing and elucidating the dynamics of virus-membrane interaction via plasma membrane mimics

    Författare :Konrad Thorsteinsson; Marta Bally; Hudson Pace; Gisa Gerold; Susan Daniel; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Plasma membrane; supported lipid bilayer; binding kinetics; equilibrium fluctuation analysis; TIRF; FRET; norovirus; HSV; SARS-CoV-2; histo-blood group antigens; ApoE; heparan sulfate; mikrobiologi; Microbiology;

    Sammanfattning : Virus infection is initiated by the attachment of a virion to a susceptible cell’s plasma membrane, in a highly dynamic and well-orchestrated process that encompasses various steps and engages numerous viral and cellular factors. These dynamic steps may include initial non-specific binding to ubiquitous cell-membrane ligands, diffusion across the membrane to a suitable entry site and virus engagement with various receptors and co-receptors on the cell surface. LÄS MER

  3. 22. On semirigid binuclear ruthenium complexes and DNA : binding modes and kinetics

    Författare :Fredrik Westerlund; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; binding kinetics; polarized light spectroscopy; threading; intercalation; SDS-sequestered dissociation; FRET; DNA; ruthenium complexes;

    Sammanfattning : .... LÄS MER

  4. 23. Chromophores for visualisation of nucleic acid recognition processes

    Författare :Marcus Wilhelmsson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DNA base analogue; chromophore aggregation; DNA-PNA-duplex stability; genetic screening; cyanine dyes; flourescence quantum yield; PNA; FRET;

    Sammanfattning : .... LÄS MER

  5. 24. Tailoring Fluorescent Probes for Organelle-Specific Imaging and Sensing

    Författare :Xin Zhang; Zhangjun Hu; Kajsa Uvdal; Fredrik Almquist; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Fluorescent imaging; Ratiometric Nanoprobe; Autophagy; Apoptosis; FRET; Fluorescerande avbildning; Ratiometric Nanoprobe; Autophagy; Apoptosis; FRET;

    Sammanfattning : Exploring and visualizing biological and pathological processes in living cells are useful for both fundamental research and applications. An understanding on the molecular level for these processes with focus on tracking biomarkers, collecting information about their surroundings, and uncovering essential molecular pathways and functions in live cells are of vital interest for cell biological study and clinical diagnosis application. LÄS MER

  7. 25. Modeling Biochemical Network Involved in Striatal Dopamine Signaling

    Författare :Anu G. Nair; Jeanette Hellgren Kotaleski; Omar Gutierrez Arenas; Upinder Singh Bhalla; Jakob Kisbye Dreyer; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dopamine signaling; Striatum; Reward learning; Acetylcholine; Mass-action modeling; FRET biosensor; Adenosine; Eligibility trace; Computer Science; Datalogi;

    Sammanfattning : In this thesis, I studied the molecular integration of reward-learning related neuromodulatory inputs by striatal medium-sized projection neurons (MSNs) using mass-action kinetic modeling.It is known that, in reward learning, an unexpected reward results in transient elevation in dopamine (peak) whereas omission of an expected reward leads to transient dopamine decrease (dip). LÄS MER