Sökning: "DNA base analogue"
Visar resultat 1 - 5 av 6 avhandlingar innehållade orden DNA base analogue.
1. DNA and RNA base analogue FRET - from fluorophore design to biochemical applications
Sammanfattning : This thesis focuses on the development and use of fluorescent base analogues (FBAs). They are important tools in research concerning nucleic acids structure, dynamics and interactions. LÄS MER
2. Expanding the alphabet of fluorescent nucleic acid base analogues: Characterization of new members
Sammanfattning : Fluorescence has proven to be a powerful tool for studying structure, dynamics and interactions of biomolecules such as proteins, RNA and DNA. However, since the natural DNA/RNA nucleobases are virtually non-fluorescent, there is a need for developing fluorescent nucleic acid markers. LÄS MER
3. Fluorescent Nucleobase Analogues and their use for Investigating DNA Interactions
Sammanfattning : Ever since unravelling the structure of DNA, an expanding research field has emerged with ongoing efforts dedicated to increase our understanding of the molecule of life. Since the natural nucleobases are virtually non-emissive, it has been a challenge for decades to ‘light up’ DNA/RNA in order to investigate their properties utilizing fluorescence techniques. LÄS MER
4. Recognition and Visualization of Nucleic Acids
Sammanfattning : The work presented in this Thesis focuses on the interaction between nucleic acids and small molecules, as well as binding or incorporation of reporter chromophores into nucleic acids. The results could help in studying and understanding processes that are fundamental to describe mechanisms behind a genetic disorder. LÄS MER
5. Chromophores for visualisation of nucleic acid recognition processes
Sammanfattning : .... LÄS MER
