Sökning: "Konrad Thorsteinsson"

Hittade 1 avhandling innehållade orden Konrad Thorsteinsson.

1. 1. Probing and elucidating the dynamics of virus-membrane interaction via plasma membrane mimics

   Författare :Konrad Thorsteinsson; Marta Bally; Hudson Pace; Gisa Gerold; Susan Daniel; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Plasma membrane; supported lipid bilayer; binding kinetics; equilibrium fluctuation analysis; TIRF; FRET; norovirus; HSV; SARS-CoV-2; histo-blood group antigens; ApoE; heparan sulfate; mikrobiologi; Microbiology;

   Sammanfattning : Virus infection is initiated by the attachment of a virion to a susceptible cell’s plasma membrane, in a highly dynamic and well-orchestrated process that encompasses various steps and engages numerous viral and cellular factors. These dynamic steps may include initial non-specific binding to ubiquitous cell-membrane ligands, diffusion across the membrane to a suitable entry site and virus engagement with various receptors and co-receptors on the cell surface. LÄS MER