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Visar resultat 1 - 5 av 8 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Mathematical modelling in upper secondary school in Sweden : An exploratory investigation

   Författare :Peter Frejd; Christer Bergsten; Jonas Ärlebäck Bergman; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MATHEMATICS; MATEMATIK;

   Sammanfattning : The official curriculum guidelines for upper secondary school in Sweden emphasise the use of mathematical models and mathematical modelling in mathematics education. However, no explicit definitions or descriptions of the notions are given in the curriculum. LÄS MER

3. 2. Encountering Evolution : Children's Meaning-Making Processes in Collaborative Interactions

   Författare :Johanna Frejd; Magnus Hultén; Karin Stolpe; Konrad Schönborn; Christina Siry; Linköpings universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Meaning-making processes; Science Education; Evolution; Multimodality; Collaborative Interaction; Exploratory studies; Meningsskapandeprocesser; Naturvetenskapsundervisning; Evolution; Multimodalitet; Interaktion; Explorativa studier;

   Sammanfattning : This thesis explores preschool class children’s meaning making processes when they encounter evolution. By adopting social semiotic and sociocultural perspectives on meaning making, three group-based tasks were designed. Video data from the activities were analysed using a multimodal approach. LÄS MER

4. 3. Modes of Mathematical Modelling : An analysis of how modelling is used and interpreted in and out of school settings

   Författare :Peter Frejd; Christer Bergsten; Jonas Ärlebäck Bergman; Rudolf Strässer; Linköpings universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : The relevance of using mathematics in and for out-of-school activities is one main argument for teaching mathematics in education. Mathematical modelling is considered as a bridge between the mathematics learned and taught in schools and the mathematics used at the workplace and in society and it is also a central notion in the present Swedish mathematical syllabus for upper secondary school. LÄS MER

5. 4. Synthesis of β-turn and pyridine based peptidomimetics

   Författare :David Blomberg; Jan Kihlberg; Kay Brickmann; Torbjörn Frejd; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Peptidomimetics; beta-turn; beta-strand; pyridine scaffold; Grignard exchange reaction; SNAr reaction; thrombin inhibitor; Leu-enkephalin.; Organic synthesis; Organisk syntes;

   Sammanfattning : Despite the unfavorable pharmacokinetic properties associated with peptides, they are still of great interest in drug development due to a multitude of interesting biological functions. The development of peptidomimetics strives to maintain or improve the biological activity of a peptide concurrently with removing the unwanted properties. LÄS MER

7. 5. Cellular Studies of HER-family Specific Affibody Molecules

   Författare :Lovisa Göstring; Lars Gedda; Jörgen Carlsson; Fredrik Frejd; Håkan Hedman; Uppsala universitet; []
   Nyckelord :EGFR; HER2; HER3; Affibody; internalisation; tumour targeting; MEDICINE; MEDICIN;

   Sammanfattning : The human epidermal growth-factor like receptor (HER) family of receptor tyrosine kinases are important targets for cancer therapy. The family consists of four members - EGFR, HER2, HER3 and HER4 - that normally transfer stimulatory signals from extracellular growth factors to the intracellular signalling network. LÄS MER