Sökning: "pyridine scaffold"
Hittade 3 avhandlingar innehållade orden pyridine scaffold.
Sammanfattning : Despite the unfavorable pharmacokinetic properties associated with peptides, they are still of great interest in drug development due to a multitude of interesting biological functions. The development of peptidomimetics strives to maintain or improve the biological activity of a peptide concurrently with removing the unwanted properties. LÄS MER
2. Design and Synthesis of a Tripeptidomimectic Scaffold Based on Pyridine. Applications to the PLG Neuropeptide
Sammanfattning : .... LÄS MER
3. Design and Synthesis of Novel Glutamine Synthetase Inhibitors and Development of Palladium(0)-Catalyzed Aminocarbonylation
Sammanfattning : Tuberculosis (TB) is a major infectious disease, killing about 2 million people annually throughout the world. Today's TB treatment is a lengthy procedure involving a combination of antibiotics. No new TB drug has been introduced onto the market in the past 40 years, and the emergence of multi- and extensively drug-resistant TB calls for new drugs. LÄS MER