Sökning: "extracellular proteins"

Visar resultat 16 - 20 av 593 avhandlingar innehållade orden extracellular proteins.

1. 16. Fluid biomarkers of extracellular matrix remodelling across neurological diseases

   Författare :Karolina Minta; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; biomarker; extracellular matrix; idiopathic normal pressure hydrocephalus; immunoassay; mass spectrometry; radiation-induced brain injury; traumatic brain injury; vascular dementia;

   Sammanfattning : Neurological diseases constitute a major health and socioeconomic issue. Despite an enormous amount of research going on globally, the prevalence and mortality of neurological disorders are still rising. LÄS MER

3. 17. Structure and Interactions of the Extracellular Matrix Protein PRELP

   Författare :Eva Bengtsson; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reumatologi; muskelsystem; Skelett; extracellular matrix; PRELP; heparin; heparan sulfate; perlecan; collagen; cell-binding; Skeleton; rheumatology locomotion; muscle system; Biochemistry; Metabolism; Biokemi;

   Sammanfattning : This thesis describes the structure and interactions of a novel extracellular matrix protein - PRELP (proline arginine-rich end leucine-rich repeat protein). The amino acid sequence of PRELP showed that it belonged to the leucine-rich repeat (LRR) protein family in connective tissues. LÄS MER

4. 18. Intracellular components involved in parathyroid sensing of extracellular calcium

   Författare :Isaac G. Onyango; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Parathyroid hormone; secretion; Src kinase; ERK; PI 3-kinase; PKC; extracellular calcium; parathyroid cell; Biokemi; Biochemistry; Biokemi; Medical and Physiological Chemistry; medicinsk och fysiologisk kemi;

   Sammanfattning : Parathyroid glands are the primary regulator of extracellular calcium ([Ca2+]e). Ca2+ plays a key role in many fundamental biological processes and is also an essential structural component of the skeleton. The parathyroid chief cells detect small changes in [Ca2+]e and respond by altering the secretion of parathyroid hormone (PTH). LÄS MER

5. 19. Interactions between extracellular matrix proteins and the complement system - In the perspective of cartilage degradation in inflammatory joint diseases

   Författare :Camilla Melin Fürst; Malmö Proteinkemi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Complement system; rheumatoid arthritis; osteoarthritis; extracellular matrix; cartilage degradation; mass spectrometry;

   Sammanfattning : Abstract: The joint diseases osteoarthritis and rheumatoid arthritis are characterized by destructive inflammatory processes that result in pathological changes of the joint tissues, including proteolytic degradation of cartilage and release of extracellular matrix proteins or fragments to the synovial fluid. The complement system, which is a part of the innate immune system, plays a central role in promoting the joint inflammation in these diseases. LÄS MER

7. 20. Cellular and Molecular Responses to Traumatic Brain Injury

   Författare :Camilla Lööv; Anna Erlandsson; M. Elly Hol; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Traumatic Brain Injury; Astrocyte; Apoptosis; Biomarkers; Ezrin; Actin; Extracellular Proteins; Degradation; Lysosome; Antigen Presentation; Neuroscience; Neurovetenskap; Neurosurgery; Neurokirurgi;

   Sammanfattning : Traumatic brain injury (TBI) is a relatively unknown disease considering the tens of millions of people affected around the world each year. Many TBI patients die from their injuries and survivors often suffer from life-long disabilities. LÄS MER