Sökning: "dorsal horn"

Visar resultat 41 - 45 av 47 avhandlingar innehållade orden dorsal horn.

  1. 41. Nerve injury induced pain and spinal cord stimulation

    Författare :Camilla Ultenius; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Neuropathic pain;

    Sammanfattning : Chronic neuropathic pain caused by injury to or disease in the nervous system is relatively common and results in major suffering, poor quality of life and incapacity. Such pain is a therapeutic challenge because a considerable portion of the patients fails to benefit from pharmacotherapy. LÄS MER

  3. 42. Experimental nerve injury : induced pain : mechanisms and modulation

    Författare :Johan Wallin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic nerve injury-induced pain presents a therapeutic challenge since such pain is often resistant to conventional analgesic drugs including opioids. Better knowledge of the pathophysiological mechanisms underlying nerve injuryinduced pain is necessary to develop new and more efficacious therapies. LÄS MER

  4. 43. Spinal Acetylcholine Release : Mechanisms and Receptor Involvement

    Författare :Mahinda Kommalage; Urban Höglund; Ernst Brodin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; acetylcholine release; spinal antinociception; nicotinic receptor; serotonin; GABA; Neurovetenskap; Neurology; Neurologi;

    Sammanfattning : Impulses coming from peripheries are modified in the spinal cord and transmitted to the brain. Several neurotransmitters have been involved in the processing of impulses in the spinal dorsal horn. Acetylcholine (ACh) is one of many neurotransmitters involved in the regulation of nociception in the spinal cord. LÄS MER

  5. 44. An exploration of the mechanisms behind peripheral nerve injury

    Författare :Rebecca Wiberg; Liudmila Novikova; Paul Kingham; Ash Mosahebi; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peripheral nerve injury; target organ; spinal motoneurons; primary sensory neurons; degeneration; anatomi; Human Anatomy;

    Sammanfattning : Despite surgical innovation, the sensory and motor outcome after peripheral nerve injury is incomplete. In this thesis, the biological pathways potentially responsible for the poor functional recoveries were investigated in both the distal nerve stump/target organ, spinal motoneurons and dorsal root ganglia (DRG). LÄS MER

  7. 45. Neuronal mechanisms of feedback postural control

    Författare :Li-Ju Hsu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :postural control; equilibrium; body configuration; reticulospinal neurons; stretch receptor neurons; galvanic vestibular stimulation; artificial feedback; locomotion; spinalization; rabbit; lamprey;

    Sammanfattning : Different species maintain a basic body posture due to the activity of the postural control system. An efficient control of the body orientation, as well as the body configuration, is important for standing and during locomotion. LÄS MER