Sökning: "dna probe"

Visar resultat 41 - 45 av 121 avhandlingar innehållade orden dna probe.

1. 41. Genome-wide epigenetic profiling of B cell leukemia and lymphoma

   Författare :Mohammad Hamdy Abdelrazak Morsy; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CLL; PRC2; EZH2; Epigenetics; CpG islands; DNA methylation; ChIP-seq; RNA-seq;

   Sammanfattning : Epigenetic modifications, at the level of DNA methylation and post-translational modifications of histone tails cooperatively function in the organization of the genome, and thereby establish the gene expression profiles, phenotypes, and cellular fates. In this work, we investigated the aberrant epigenome in chronic lymphocytic leukemia (CLL) which is one of the most frequent lymphoid malignancies in the west including the Nordic countries. LÄS MER

3. 42. Development of molecular techniques for fungal diagnostic research

   Författare :Qing-Yin Zeng; Åsa Rasmuson-Lestander; Xiao-Ru Wang; Aino Nevalainen; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Fungi; DNA markers; Aerosols; Detection and quantification; Environmental monitoring; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

   Sammanfattning : Fungi are present everywhere in indoor and outdoor environments. Many fungi are toxigenic or pathogenic that may cause various public health concerns. Rapid detection, quantification and characterization of fungi in living and working environments are essential for exposure risk assessment to safe guard public health. LÄS MER

4. 43. Single Molecule Detection : Microfluidic Automation and Digital Quantification

   Författare :Malte Kühnemund; Mats Nilsson; Ulf Landegren; Sten Linnarsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; single molecule; digital; rolling circle amplification; magnetic particle; padlock probe; microfluidics; resistive pulse sensing; lab on chip; mobile phone microscopy; enrichment; sequencing;

   Sammanfattning : Much of recent progress in medical research and diagnostics has been enabled through the advances in molecular analysis technologies, which now permit the detection and analysis of single molecules with high sensitivity and specificity. Assay sensitivity is fundamentally limited by the efficiency of the detection method used for read-out. LÄS MER

5. 44. Molecular Recognition Materials Synthesized Based on Small molecules, DNA, and Imprinted Polymers for Bioanalytical Applications

   Författare :Xiaoting Xue; Tillämpad biokemi; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; detection; molecularly imprinted polymers; boronic acid; DNA; dendritic fibrous nanosilica;

   Sammanfattning : The development of sensitive, convenient, and cost-effective methods for detecting disease biomarkers is very important for meeting the growing demand for early clinical diagnosis. Additionally, the detection of disease biomarkers at ultralow concentrations is very important for disease prevention and treatment and posttreatment rehabilitation. LÄS MER

7. 45. Cell cycle regulation and DNA damage response : a record of polo-like kinase 1 activity

   Författare :Elvira Hukasova; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Division and cell proliferation is an essence of life. A human cell has in its core a very simple yet a very complex machinery to coordinate cell cycle activities and events. LÄS MER