Sökning: "diabetes CD14"
Visar resultat 1 - 5 av 6 avhandlingar innehållade orden diabetes CD14.
1. Sex differences in immune response and sex hormone receptor expression in healthy individuals and during viral infection
Sammanfattning : There is sex-bias in morbidity and mortality from infectious diseases. Infections kill more men than women and several studies have pointed out differences in the immune system as a reason. The sex hormones estrogen, progesterone and testosterone all shape the effect of the immune response on multiple levels. LÄS MER
2. Studies on receptors for modified LDL in human monocytes and macrophages : a link between diabetes and atherosclerosis?
Sammanfattning : Type 2 diabetes increases the risk for cardiovascular disease three- to fourfold. Because of the rise in diabetes prevalence there is a need for a better understanding of the link between diabetes and atherosclerosis. LÄS MER
3. Characterization of Pleiotropic Activities of alpha1-Antitrypsin
Sammanfattning : Chronic Obstructive Pulmonary Disease (COPD) is a respiratory disease characterized by chronic inflammatory response in the airways and lung parenchyma that involves the influx of inflammatory, structural cells and mediators. The inflammatory process resulting in lung tissue destruction, emphysema, includes the excess of uninhibited proteases released from inflammatory cells. LÄS MER
4. Vitamin D insufficiency in cystic fibrosis : prevalence, consequences and intervention
Sammanfattning : Cystic fibrosis (CF) is the most common life-shortening autosomal recessive disease in Caucasians. The major cause of morbidity and mortality is lung disease, characterized by a vicious circle of infection and inflammation. LÄS MER
5. Genetic variation of tight junction structures in intestinal inflammation
Sammanfattning : The epithelial barrier facing the external environment in the gastrointestinal (GI) tract is comprised of several components, including the tight junction (TJ) structures observed for the first time in 1963. TJ structures, which are multiprotein complexes composed of transmembrane proteins and a diverse spectrum of intracellular components, create a primary barrier to diffusion of ions, solutes, and water and they concomitantly prevent permeation of pro-inflammatory factors, such as pathogens, toxins, and antigens. LÄS MER