Sökning: "scavenger receptor"
Visar resultat 1 - 5 av 47 avhandlingar innehållade orden scavenger receptor.
Sammanfattning : Low plasma levels of high-density lipoprotein (HDL) and high levels of low-density lipoprotein (LDL) are well-recognized risk factors for cardiovascular disease. The uptake and degradation of LDL cholesterol have been characterized in detail at the molecular level. Less is known about the metabolism and cellular uptake of HDL cholesterol. LÄS MER
Sammanfattning : The respiratory system of Drosophila melanogaster, the trachea, is widely used as a model system to study the development of branched tubular organs. Airway maturation in Drosophila entails a series of sequential events: first, a massive apical secretion of luminal proteins initiates diametric tube expansion, second an endocytic wave removes luminal proteins and finally liquid clearance and gas filling converts the nascent epithelial tubes to a functional respiratory organ. LÄS MER
Sammanfattning : Macrophages are monocyte-derived cells that play an important role in the innate immune response against invading pathogens. These cells express several host defense receptors that can be divided into two classes; those dependent on opsonizing components for recognition of pathogens, and those that can recognize pathogens directly, pattern recognition receptors (PRRs). LÄS MER
Sammanfattning : Innate immunity, the first line of defense against infectious microorganisms, appeared early in evolution. Innate immunity relies on specialized cells such as macrophages that are the first to encounter pathogens during infection. LÄS MER
5. Studies on receptors for modified LDL in human monocytes and macrophages : a link between diabetes and atherosclerosis?
Sammanfattning : Type 2 diabetes increases the risk for cardiovascular disease three- to fourfold. Because of the rise in diabetes prevalence there is a need for a better understanding of the link between diabetes and atherosclerosis. LÄS MER