Sökning: "cytoplasmic and nuclear"

Visar resultat 41 - 45 av 122 avhandlingar innehållade orden cytoplasmic and nuclear.

  1. 41. Control of human papillomavirus type 1 late mRNA stability and translation by an AU-rich RNA element

    Författare :Marcus Sokolowski; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; HPV-1; HPV-16; late genes; 3´ UTR; L1; L2; c-fos; AU rich element; HuR; hnRNP C1 C2; mRNA stability; translation; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Sammanfattning : Human Papillomaviruses (HPVs) infect the epithelial tissues in humans and infection with certain high-risk types is associated with cancer. The expressionof the HPV late capsid genes is dependent on cell differentiation. This may be one reason for the lack of HPV replication in vitro. LÄS MER

  3. 42. Nucleoporins and Protein Transport in Drosophila

    Författare :Peggy Roth; Christos Samakovlis; Volker Cordes; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NPC; Nucleoporin; Nup88; Nup214; CRM1; Dorsal; Drosophila; Developmental biology; Utvecklingsbiologi;

    Sammanfattning : Many biological responses rely on the selective translocation of transcriptional regulators in and out of the nucleus through nuclear pore complexes (NPC). More than one million macromolecules per minute pass through the NPC and an important challenge is to understand the coordination of nucleocytoplasmic trafficking. LÄS MER

  4. 43. Studies of mRNA transport and localization

    Författare :Chandrasekhar Saki Raju; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : During mRNA biogenesis, a subset of newly exported mRNA is assembled into larger RNA granules which are transported to subcellular compartments for localized translation. These mechanisms are critical for asymmetric mRNA and protein distribution and have profound impact on cellular physiology. LÄS MER

  5. 44. Enabling massive genomic and transcriptomic analysis

    Författare :Henrik Stranneheim; Joakim Lundeberg; Elaine Mardis; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DNA; RNA; sequencing; massively parallel sequencing; alignment; assembly; single nucleotide polymorphism; LHON;

    Sammanfattning : In recent years there have been tremendous advances in our ability to rapidly and cost-effectively sequence DNA. This has revolutionized the fields of genetics and biology, leading to a deeper understanding of the molecular events in life processes. LÄS MER

  7. 45. Expression of ras and p53, DNA ploidy and 5-phase fraction in human colorectal adenocarcinoma

    Författare :Xiao-Feng Sun; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The accumulation of oncogene and anti-oncogene alterations play an important role in the development of colorectal adenocarcinomas. These specific gene alterations cause changes of DNA ploidy and cell proliferation and, in turn, DNA instability might lead to more genetic changes. LÄS MER