Sökning: "colorectal cancer CRC"

Visar resultat 16 - 20 av 125 avhandlingar innehållade orden colorectal cancer CRC.

1. 16. Creating access to cancer care : an exploration of patient-provider encounters in primary care, and sociodemographic factors

   Författare :Cecilia Hultstrand; Senada Hajdarevic; Anna-Britt Coe; Mikael Lilja; Kristina Bengtsson Boström; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Access to care; patient-provider interaction; primary care; encounters; experiences; cancer; time to diagnosis; standardization; sociodemographic factors;

   Sammanfattning : Background: Access to care is widely discussed in both research and practice. However, previous research about access to care has mainly focused on individual behaviors of seeking care, and theories about access have mostly focused on quantifiable dimensions, such as supply and demand. LÄS MER

3. 17. Prognostic role of tumour associated trypsin inhibitor in colorectal cancer patients

   Författare :Alexander Gaber; Tumörmikromiljö; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; KRAS mutation; ERK1 2; TATI; Colorectal cancer; Prognosis; Biomarker; EGFR; STAT3;

   Sammanfattning : Colorectal cancer (CRC) is one of the most common forms of human cancer worldwide with approximately 1 million new cases detected every year. CEA is currently the only accepted CRC marker incorporated into clinical practice, where it is used for early detection of metastasis in follow-up of patients having stage II and III disease, and for monitoring response to adjuvant treatment. LÄS MER

4. 18. Molecular understanding of KRAS- and BRAF-mutated colorectal cancers

   Författare :Ida Lundberg; Richard Palmqvist; Maria Wikberg; Sofia Edin; Anita Sjölander; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; BRAF; KRAS; SOX2; CDX2; cancer stem cell; Th1 lymphocytes; miRNA; prognosis;

   Sammanfattning : Colorectal cancer (CRC) is the third most commonly diagnosed malignancy in both men and women, and one of the leading causes of cancer-related deaths worldwide. One frequently mutated pathway involved in oncogenesis in CRC is the RAS/RAF/MAP kinase pathway. LÄS MER

5. 19. A cohort study of sex differences and prognostic biomarkers in colorectal cancer

   Författare :Sakarias Wangefjord; Tumörmikromiljö; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; prognosis; treatment prediction; biomarkers; sex differences; cyclin D1; microsatellite instability; beta-catenin; KRAS mutation; BRAF mutation; EGFR expression; EGFR gene copy number alterations;

   Sammanfattning : Colorectal cancer (CRC) is one of the most common forms of cancer worldwide, with an annual incidence of more than 1 million cases. Despite advancements in the management of CRC, mortality remains high. LÄS MER

7. 20. Molecular and Biological Characteristics of Stroma and Tumor Cells in Colorectal Cancer

   Författare :Jingfang Gao; Xiao-Feng Sun; Richard Palmqvist; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Carcinogenesis; genetic alterations; colorectal cancer CRC ; cysteine-histidine rich protein PINCH ; Inflammatory infiltration; Angiogenesis; lymphangiogenesis; Oncology; Onkologi;

   Sammanfattning : Carcinogenesis is a progressive process involving multiple genetic alterations in tumor cells and complex interactions in the tumor-host microenvironment. To better understand the contribution of molecular alterations in tumor cells and stromal variables to the development of colorectal cancer (CRC) and identify prognostic factors, in this study we examined the clinicopathological and biological significance of stromal variables, including particularly interesting new cysteine-histidine rich protein (PINCH), inflammatory infiltration, angiogenesis and lymphangiogenesis, as well as hRAD50/hMRE11/hNBS1 proteins and hRAD50 mutation in tumor cell in CRC. LÄS MER