Sökning: "chemical biology"

Visar resultat 31 - 35 av 552 avhandlingar innehållade orden chemical biology.

  1. 31. Fucoidan-Mimetic Glycopolymers : Synthesis and Biomedical Applications

    Författare :Mattias Tengdelius; Peter Konradsson; May Griffith; Peter Påhlsson; Mats Johansson; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The marine polysaccharide fucoidan has demonstrated several interesting biological properties, for instance being antiviral, anticoagulant, anti-inflammatory, anticancer, and platelet activating. Many of these properties are desirable for various biomedical applications. Yet, there are few reports on fucoidan being used in such applications. LÄS MER

  2. 32. Methods for elucidating membrane protein structure and function

    Författare :Carolina Trkulja; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; patch clamp; antibodies; mass spectrometry; ion channels; proteomics; fluorescence; TRPV1; cholesterol.; limited proteolysis; Membrane proteins;

    Sammanfattning : Elucidation of the structure-function relationship of membrane proteins increases our understanding of many biological processes, both physiological and pathological. However, membrane proteins have been notoriously difficult to study, having part of their structure embedded into the lipid cell membrane. LÄS MER

  3. 33. Signal Transduction in Photoreceptor Proteins : Insights From Time-Resolved X-ray Solution Scattering

    Författare :Oskar Berntsson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Signal transduction; Photoreceptor; Time-resolved X-ray solution scattering; Protein dynamics; Phytochrome; Light-oxygen-voltage; Cryptochrome;

    Sammanfattning : The ability to sense and react to different light conditions is of great importance for many organisms on the face of the earth. Specialized proteins known as photoreceptor proteins provide bacteria, plants and animals with this ability. LÄS MER

  4. 34. The cross-talk of iron and ascorbate -Complexation and intracellular regulation of transport in human enterocytes

    Författare :Nathalie Scheers; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NRAMP2; ascorbate; ferroportin; ferritin; iron; SVCT1; DCYTB;

    Sammanfattning : Iron deficiency is a serious health issue in developing countries and also in vulnerable groups of the industrialized world. There are several ways to address this issue. The present approach was to learn more about the basic mechanisms of iron uptake in the presence of ascorbate, one of the best enhancers of iron absorption. LÄS MER

  5. 35. Tailoring Fluorescent Probes for Organelle-Specific Imaging and Sensing

    Författare :Xin Zhang; Zhangjun Hu; Kajsa Uvdal; Fredrik Almquist; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Fluorescent imaging; Ratiometric Nanoprobe; Autophagy; Apoptosis; FRET; Fluorescerande avbildning; Ratiometric Nanoprobe; Autophagy; Apoptosis; FRET;

    Sammanfattning : Exploring and visualizing biological and pathological processes in living cells are useful for both fundamental research and applications. An understanding on the molecular level for these processes with focus on tracking biomarkers, collecting information about their surroundings, and uncovering essential molecular pathways and functions in live cells are of vital interest for cell biological study and clinical diagnosis application. LÄS MER