Sökning: "chemical biology"
Visar resultat 21 - 25 av 549 avhandlingar innehållade orden chemical biology.
21. Computational Protein Evolution : Modeling the Selectivity and Promiscuity of Engineered Enzymes
Sammanfattning : Enzymes are biological catalysts that significantly increase the rate of all biochemical reactions that take place within cells and are essential to maintain life. Many questions regarding their function remain unknown. LÄS MER
22. UDP-sugar metabolizing pyrophosphorylases in plants : formation of precursors for essential glycosylation-reactions
Sammanfattning : UDP-sugar metabolizing pyrophosphorylases provide the primary mechanism for de novo synthesis of UDP-sugars, which can then be used for myriads of glycosyltranferase reactions, producing cell wall carbohydrates, sucrose, glycoproteins and glycolipids, as well as many other glycosylated compounds. The pyrophosphorylases can be divided into three families: UDP-Glc pyrophosphorylase (UGPase), UDP-sugar pyrophosphorylase (USPase) and UDP-N-acety lglucosamine pyrophosphorylase (UAGPase), which can be discriminated both by differences in accepted substrate range and amino acid sequences. LÄS MER
23. Theoretical Study on Chemical Structures and Stability of Molecules in Metallic Junctions
Sammanfattning : In this thesis, we focus on the structural identification of the interface using surface enhanced Raman spectroscopy (SERS) and inelastic electron tunnelling scattering (IETS). Two different molecular junctions, namely gold/ trans-1,2-bis (4-pyridyl) ethylene/gold junction and gold/4,4'-bipyridine/gold junctions in various conditions were studied and the corresponding configurations were determined. LÄS MER
24. Methods development for metaproteomics-guided bioprospecting of novel enzymes
Sammanfattning : Industrial biotechnology has been announced by several organizations and governments as a key enabling technology for the enhanced economic growth in a low-carbon and knowledge-based bioeconomy. An important goal to promote an environment friendly and sustainable industrial biotechnology is the discovery of new enzymes. LÄS MER
25. Lignin-carbohydrate complexes: Model compounds synthesis
Sammanfattning : In lignocellulose there is a recalcitrant interaction by covalent and non-covalent bonds called the lignin-carbohydrate complex. This interaction has been the subject of studies trying to unveil its chemical structure, to understand the mechanims involved in its formation and to determine its influence on practical applications such as the process of turning biomass into ethanol. LÄS MER