Sökning: "in vitro reprogramming"
Visar resultat 1 - 5 av 36 avhandlingar innehållade orden in vitro reprogramming.
1. Cell reprogramming as a way to produce new functional neurons
Sammanfattning : .... LÄS MER
2. Generation of induced neurons via direct conversion in vivo and in vitro
Sammanfattning : Cellular reprogramming is when one cell is changed into another. This involves structural modifications on the DNA of a cell resulting in a transcriptional change. This occurs naturally during development when early pluripotent cells gradually differentiate into more specialized cells that finally result in a complete organism. LÄS MER
3. Functional and Transcriptional Studies of Human Dopaminergic Neurons
Sammanfattning : Parkinson’s Disease (PD) is the most common movement disorder and second most common neurodegenerative disease. The principal hallmark of the pathology is represented by a loss of mesencephalic Dopaminergic neurons (mesDA) that reside in the Substantia Nigra pars compacta (SNpc). LÄS MER
4. Generation of cortical neurons through reprogramming technology
Sammanfattning : The human cortex is affected by several debilitating acute and chronic neurodegenerative disorders such as stroke, traumatic brain injury, amyotrophic lateral sclerosis and Alzheimer’s disease, which target specific types of cortical neurons. Emerging evidence indicates that stem cells and reprogrammed cells can be used to generate human cortical neurons both for cell replacement by transplantation, and for disease modeling and drug screening. LÄS MER
5. Networks in epigenetics
Sammanfattning : Networks are ubiquitous. It is only recently, we started exploring what purpose they serve in real world. Biological research supposedly has, and will be, benefited most from the network science because of inherent complexity embedded in its multilayered organization. LÄS MER