Sökning: "cell fate specification"

Visar resultat 6 - 10 av 48 avhandlingar innehållade orden cell fate specification.

  1. 6. FGF signaling in specification of hESC-derived definitive endoderm

    Författare :Jacqueline Ameri; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Diabetes affects around 200 million people worldwide. Curing diabetes would require the prevention of autoimmune destruction of beta cells and restoration of the beta cell mass restored either through regeneration or transplantation of the insulin producing cells. LÄS MER

  3. 7. The Role of miRNA in Neurogenesis and Cell Specification

    Författare :Malin Åkerblom; Molekylär neurogenetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; miRNA; microRNA; miR-124; miR-9; miR-125; adult neurogenesis; neural stem cells; cell specification; microglia; lentiviral vectors; olfactory bulb; olfactory bulb interneurons;

    Sammanfattning : Only a few decades ago, it was generally believed that gene expression was controlled in a unidirectional way, i.e. DNA was transcribed into RNA, which simply acted as a messenger molecule used to produce the protein that executed cellular functions. LÄS MER

  4. 8. Characterization of New Players in Planar Polarity Establishment in Arabidopsis

    Författare :Stefano Pietra; Markus Grebe; Niko Geldner; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; SABRE; planar polarity; CLASP; cell division orientation; microtubule cytoskeleton; actin; AIP1; patterning; Developmental Biology; miljömedicinsk utvecklingsbiologi;

    Sammanfattning : Coordinated polarity and differentiation of cells in the plane of a tissue layer are essential to the development of multicellular organisms. Arabidopsis thaliana root hairs and trichomes provide model systems to study the pathways that control planar polarity and cell fate specification in plants. LÄS MER

  5. 9. Cdc42 and Rac1 in Pancreatic Tubulogenesis and Islet Formation

    Författare :Gokul Kesavan; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Tubes form the basic structure of several organs like lungs, kidneys, glandular organs like the pancreas, mammary and salivary glands. Tube formation involves a series of dynamic and interdependent cellular processes, including cytoskeletal reorganization, assembly of intercellular junctional complexes, and cell polarization. LÄS MER

  7. 10. Mechanisms of Olfactory sensory neuron class maintenance in Drosophila : It is all about design and equilibrium

    Författare :Shadi Jafari; Mattias Alenius; Stefan Thor; David Engblom; Bassem Hassan; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : How the cellular diversity of our body is generated and maintained is still a great mystery regardless of the wealth of research that has been done on this issue. The greatest complexity is found in the nervous system that contains a vast number of neurons and displays a great diversity in cell types and classes. LÄS MER