Sökning: "cell fate specification"

Visar resultat 21 - 25 av 48 avhandlingar innehållade orden cell fate specification.

  1. 21. Role of transcription factors in sensory neuron specification

    Författare :Andreas Montelius; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The interface between our mind and the internal and external environments is the peripheral nervous system. A range of different sensory neuron subtypes detects cold, heat, pain, touch, and other stimuli. LÄS MER

  2. 22. DNA fragility in the context of neural stem cell fate : a multi-method integrative exploration of genome dynamics

    Författare :Roberto Ballarino; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Recent advances in mapping the complex genetic architecture underlying various debilitating brain disorders have enabled identification of several genetic risk variants. However, these risk variants only explain part of the heritability and vulnerability to these disorders in early development. LÄS MER

  3. 23. The role of Nkx proteins neuronal and glial specification

    Författare :Anna Vallstedt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : During development, different classes of neurons and glia are generated from proliferative progenitor cells lining the ventricles of the brain and the lumen of the spinal cord. A central issue in developmental neuroscience is to understand the mechanisms by which these cells are generated in space and over time. LÄS MER

  4. 24. Specification and potency of human neural stem cells for clinical transplantation

    Författare :Per Henrik Vincent; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neural stem cells hold promise for future treatment of spinal cord injury. Various aspects regarding cell fate specification, manufacturing and monitoring, with implications for clinical applications of these cells, are discussed herein. LÄS MER

  5. 25. Neuronal types and their specification dynamics in the autonomic nervous system

    Författare :Alessandro Furlan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The autonomic nervous system is formed by a sympathetic and a parasympathetic division that have complementary roles in the maintenance of body homeostasis. Autonomic neurons, also known as visceral motor neurons, are tonically active and innervate virtually every organ in our body. LÄS MER