Sökning: "aromatic substitution reaction"

Visar resultat 21 - 25 av 26 avhandlingar innehållade orden aromatic substitution reaction.

  1. 21. Hydrolysis and photolysis of brominated flame retardants and some traditional persistent organic pollutants : Reactivity as a tool in fate assessement of chemicals

    Författare :Sara Rahm; Åke Bergman; Stellan Marklund; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Environmental chemistry; Miljökemi;

    Sammanfattning : An organic compound that remains in the environment for a long time is regarded as a persistent organic pollutant (POP). Still, persistency is not a well defined property with a firm definition. Instead it is a conceptual property of chemicals for which DDT and PCB are typical representatives. LÄS MER

  3. 22. C–H activation through late transition metal cyclometallation. Addressing selectivity and reactivity problems

    Författare :Mikhail Kondrashov; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; C—H activation; cyclometallation; pincer ligands; anion exchange; bimetallic complexes; oxidative functionalisation;

    Sammanfattning : The ligand-directed C—H activation relies on a coordinating donor atom being in proximity to the C—H bond activated. Cyclometallation of 2-(1-naphthyl)-pyridine – a substrate containing both γ- and δ-positions in proximity to the directing nitrogen atom – was studied. LÄS MER

  4. 23. New Arylation Strategies Based on Organomain Group Reactivity

    Författare :Carina Sollert; Lukasz T. Pilarski; Brenton L. DeBoef; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; C-H functionalisation; catalysis; ruthenium; indole; silylation; boronate; boryl aryne; aryne distortion; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi;

    Sammanfattning : The work in this thesis describes the development of new heteroarylation methodology based on transition metal-catalysed C-H functionalisation and the properties of organomain group compounds. The underlying reaction mechanisms and reactivity patterns of the (hetero)arene substrates are also investigated. LÄS MER

  5. 24. Probing the Alpha Class Glutathione Transferase Structure. Combinatorial Subunit Studies and Rational Redesign

    Författare :Ann Gustafsson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Glutathione transferases; rational redesign; enzyme; catalysis; Biokemi; Biochemistry; Biokemi; Molecular Biotechnology; molekylär bioteknik avd f jonfysik ;

    Sammanfattning : The present work concerns two Alpha class enzymes, GST A1-1 and GST A4-4, of the glutathione transferase (GST) family, which are detoxication enzymes catalyzing the conjugation of the tripeptide glutathione with various electrophiles. The GST A1-1 structure was explored for protein engineering purposes and tailored for increased activity toward alkenals. LÄS MER

  7. 25. New Reactivity in Diaryliodonium Salt Chemistry

    Författare :Erika Linde; Berit Olofsson; Thomas Wirth; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic Chemistry; organisk kemi;

    Sammanfattning : Diaryliodonium salts (Ar2IX) have emerged as versatile multi-purpose reagents with desirable properties such as easy accessibility, low toxicity and applicability under mild and metal-free reaction conditions. Despite displaying broad utility in arylations of both carbon and heteroatom nucleophiles, the overall sustainability of these protocols is compromised by featuring poor atom economy due to the formation of stochiometric iodoarene byproducts. LÄS MER