Sökning: "abuse"

Visar resultat 16 - 20 av 461 avhandlingar innehållade ordet abuse.

  1. 16. Neuropeptide Receptors as Treatment Targets in Alcohol Use Disorders

    Författare :Abdul Maruf Asif Aziz; Annika Thorsell; David Engblom; Elizabeth Jerlhag; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Alcohol use disorder (AUD) is a complex disorder with multiple pathophysiological processes contributing to the initiation, progression and development of the disease state. AUD is a chronic relapsing disease with escalation of alcohol-intake over time in repeated cycles of tolerance, abstinence and relapse and hence, it is very difficult to treat. LÄS MER

  3. 17. Renal and parathyroid function in psychiatric patients on lithium treatment

    Författare :Hans Bendz; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetes insipidus; glomerular filtration rate; hypercalcemia; hyperparathyroidism; lithium; nephrogenic; nephropathy; polyuria;

    Sammanfattning : Aims. To investigate the prevalence and clinical implications of renal and parathyroid morbidity in lithium patients. Patients. Short-term lithium patients (n=162; average 6 treatment years) and long-term patients (n=142; average 19 treatment years) were studied cross-sectionally. LÄS MER

  4. 18. Skin and soft tissue infections among people who inject drugs. Prevalence and correlates of bacterial infections and colonization assessed through clinical and epidemiological studies

    Författare :Disa Dahlman; Lund Psykiatri; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : .... LÄS MER

  5. 19. Serotonergic aspects on high consumption of alcohol in humans. Experimental and clinical studies

    Författare :Matts Eriksson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alcohol; alcohol-dependence; serotonin; SSRI; MAO-B; DRD2 A1 A2 alleles; fenfluramine; mood;

    Sammanfattning : In animal studies an association between alcohol intake and central serotonergic function has been demonstrated. There are also evidence for altered serotonergic neurotransmission in subgroups of alcohol-dependent subjects. LÄS MER

  7. 20. Stress, Drugs and Neuroscience : Neurobiological Effects of Social Stressors and Drug Exposure in Young and Adolescent Rats

    Författare :Linnea Granholm; Ingrid Nylander; Erika Roman; Anne-Lie Svensson; Maria Ellgren; Annika Thorsell; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adolescence; alcohol exposure; amphetamine; beta-endorphin; dopamine; dynorphin; early life; endogenous opioids; enkephalin; gene expression; high-speed chronoamperometry; nociceptin orphanin FQ; radioimmunoassay; self-administration; social stress; voluntary alcohol intake; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Experiences early in life or during adolescence modulate neuronal networks in the immature brain and consequently lay the foundation for future susceptibility or resilience towards psychiatric disorders. The objective in this thesis is to understand, in part, how the surrounding environment shapes the brain of a young individual. LÄS MER