Sökning: "Target levels"

Visar resultat 21 - 25 av 1142 avhandlingar innehållade orden Target levels.

  1. 21. Resolution of inflammation as a therapeutic target for Alzheimer’s disease

    Författare :Mingqin Zhu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Alzheimer’s disease (AD) is a progressive neurodegenerative disorder, clinically manifested by memory impairment, loss of ability in conducting daily activity and increased need for care, thus causing immense suffering for the afflicted and relatives, as well as a huge economic burden to the society. Despite the existence of symptom-relieving drugs, there is no drug that can stop the progression or cure the disease. LÄS MER

  3. 22. Impact of Risk Factors and Treatment in Coronary Heart Disease

    Författare :Lena Björck; Göteborgs universitet; []
    Nyckelord :coronary disease; myocardinal infarction; risk factors; smoking; lipid levels;

    Sammanfattning : Aims: The aim of the present study was to explore how risk factors and medication influence clinical presentation and mortality in coronary heart disease (CHD) and to explain how much of the decrease in CHD mortality in Sweden that could be attributed to medical and surgical treatments, and how much to changes in cardiovascular risk factors. Subjects and methods: We included 781 consecutive patients with a first acute myocardial infarction (AMI) during the period 1994 to 2002, to investigate trends in the use of lipid-lowering treatment, and changes in serum lipids. LÄS MER

  4. 23. Chartist trading in exchange rate theory

    Författare :Carina Selander; Karl-Gustaf Löfgren; Anders Vredin; Umeå universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Chartist Trading; Foreign Exchange; Overshooting; Sterilized Intervention; Target Zone; Taylor Rules; Economics; Nationalekonomi;

    Sammanfattning : This thesis consists of four papers, of which paper 1 and 4 are co-written with Mikael Bask. Paper [1] implements chartists trading in a sticky-price monetary model for determining the exchange rate. It is demonstrated that chartists cause the exchange rate to "overshoot the overshooting equilibrium" of a sticky-price monetary model. LÄS MER

  5. 24. Elucidation of thioredoxin reductase 1 as an anticancer drug target

    Författare :William C Stafford; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cancer constantly finds ways to survive, so we must find new ways to stop it. A major attribute of cancer cells is increased oxidative stress, occurring in the form of reactive oxygen species (ROS). Basal ROS generation commonly occurs in all types of cells and is essential for normal cellular growth and function. LÄS MER

  7. 25. Fatty acid amide hydrolase - A target for anti-inflammatory therapies?

    Författare :Sandra Holt; Christopher J Fowler; Anders Bucht; Gunnar Tiger; Ruth A Ross; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; FAAH; anandamide; endocannabinoid; pH; inflammation; NSAID; Farmakologi; Pharmacological research; Farmakologisk forskning; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : Anti-inflammatory drugs are a widely used class of therapeutic agents, but the use of non-steroidal anti-inflammatory drugs (NSAID) is hampered by their gastrointestinal side-effects. Recent reports that cyclooxygenase-2 inhibitors may cause cardiovascular events underline the importance of identifying new therapeutic strategies for the treatment of inflammation. LÄS MER