Sökning: "Target levels"
Visar resultat 11 - 15 av 1139 avhandlingar innehållade orden Target levels.
11. Human copper ion transfer : from metal chaperone to target transporter domain
Sammanfattning : Many processes in living systems occur through transient interactions among proteins. Those interactions are often weak and are driven by small changes in free energy. LÄS MER
12. The gamma-tubulin meshwork as a therapeutic target
Sammanfattning : Cancer is a heterogeneous disease and treatment regime is dependent on type and location of the tumor. Several of the commonly used chemotherapeutics target the functions of the microtubules. One of the major problems with these drugs is the adverse effects associated with their use. LÄS MER
13. Exploring thioredoxin reductase as an anticancer drug target
Sammanfattning : Mammalian thioredoxin reductase (TrxR; EC 1.8.1.9) is a homodimeric NADPH-dependent selenium-containing flavoenzyme with disulfide oxidoreductase activity. LÄS MER
14. Inflammation as a therapeutic target for Alzheimer's disease
Sammanfattning : Alzheimer's disease (AD) is a progressive neurodegenerative disorder which is characterised by impairment of memory and learning. The impairment is caused by neuronal death which originates in the parts of the brain that execute memory functions: the entorhinal cortex and hippocampus. LÄS MER
15. Comprehensive non-target screening to find and identify new biomagnifying organic contaminants in Baltic Sea top consumers
Sammanfattning : The development of industrial processes in the 19th and 20th centuries, in particular oil refining, resulted in a huge discovery and subsequent large-scale production of a variety of chemicals. These useful chemicals supposedly made the everyday lives of people easier and better by, for instance, controlling the spread of diseases such as malaria, through the use of DDT and other organochlorine pesticides (OCPs). LÄS MER