Sökning: "NSAID"

Visar resultat 1 - 5 av 47 avhandlingar innehållade ordet NSAID.

1. 1. Surgery for rectal cancer : the impact of perioperative factors

   Författare :Daniel Kverneng Hultberg; Martin Rutegård; Jörgen Rutegård; Peter Matthiessen; Markku Haapamäki; Lydrup Marie-Louise; Tom Öresland; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rectal cancer; abdominal surgery; anastomotic leakage; anastomotic dehiscence; postoperative complications; vascular tie; ligation level; oncologic outcome; surgical oncology; survival; recurrence; functional outcome; urogenital; anorectal; incontinence; NSAID; COX; Surgery; kirurgi;

   Sammanfattning : Rectal cancer is one of the most common and deadly cancer forms worldwide. A large proportion of rectal cancer patients are surgically treated with curative intention, with anterior resection being the most frequently used method today. LÄS MER

3. 2. Perforations of the Upper Gastro-Intestinal Tract

   Författare :Michael Hermansson; Lund Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; orthopaedics; Prognostic factors; Incidence; Surgery; Diagnostic methods; Proton pump inhibitors; NSAID; Peptic ulcer perforation; Esophageal perforation; traumatology; Kirurgi; ortopedi; traumatologi;

   Sammanfattning : Material and methods: In all, 237 consecutive patients with a perforated peptic ulcer admitted from 1974-1992 and 125 consecutive patients with an oesophageal perforation admitted from 1970-2006 to Lund University hospital were studied retrospectively. Prognostic factors were evaluated using the Cox proportional hazards model. LÄS MER

4. 3. Fatty acid amide hydrolase - A target for anti-inflammatory therapies?

   Författare :Sandra Holt; Christopher J Fowler; Anders Bucht; Gunnar Tiger; Ruth A Ross; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; FAAH; anandamide; endocannabinoid; pH; inflammation; NSAID; Farmakologi; Pharmacological research; Farmakologisk forskning; medicinsk farmakologi; Medical Pharmacology;

   Sammanfattning : Anti-inflammatory drugs are a widely used class of therapeutic agents, but the use of non-steroidal anti-inflammatory drugs (NSAID) is hampered by their gastrointestinal side-effects. Recent reports that cyclooxygenase-2 inhibitors may cause cardiovascular events underline the importance of identifying new therapeutic strategies for the treatment of inflammation. LÄS MER

5. 4. Estrogen receptor and multixenobiotic resistance genes in freshwater fish and snails: identification and expression analysis after pharmaceutical exposure

   Författare :Cecilia Hultin; Miljövetenskap; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; EE2; NSAID; estrogen receptor; oestrogen receptor; multixenobiotic resistance; fish; gastropods;

   Sammanfattning : Pharmaceuticals are today released into aquatic environments where they can interfere with organisms' biological processes.The general research objective was to analyze how aquatic freshwater organisms are affected by exposure to pharmaceuticals that are categorized by the EU as potential risk factors to the environment (i.e. LÄS MER

7. 5. Safety of Medication in Paediatrics

   Författare :Kristina Star; Karin Nordin; I Ralph Edwards; Richard Irvin Cook; Uppsala universitet; []
   Nyckelord :paediatrics; adverse drug reaction; drug-related problem; medication error; patient safety; individual case safety reports; pharmacovigilance; medication; nurses; health care personnel; dosage form; NSAID; dosing; prescription; antipsychotic medicines; postmarketing surveillance; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Background: In paediatrics, the limited documentation to guide medication, the lack of suitable dosage forms, and the continuous development in childhood present a scenario where safety of medication is a particular challenge.Aim: To explore reported adverse drug reactions (ADRs) and the challenges in prescribing and administering medicines in paediatrics, in order to identify and suggest areas needing international surveillance within medication safety and improvement in the clinical setting. LÄS MER