Sökning: "Stigbrand"

Visar resultat 11 - 14 av 14 avhandlingar innehållade ordet Stigbrand.

  1. 11. Neurofilament light as a marker for neurodegenerative diseases

    Författare :Niklas Norgren; Torgny Stigbrand; Roland Carlsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Neurofilament protein; ELISA; Cerebrospinal fluid; Neurodegenerative diseases; Immunologi; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : Neurofilaments are the main cytoskeletal constituents in neuronal cells. They are belived to be important for maintaining the structural integrity and calibre of axons and dendrites thereby influencing the conduction velocity of nerve impulses. LÄS MER

  3. 12. Protein and mRNA Studies of Rat FA1/Pref-1/dlk

    Författare :Gabriella Persdotter Hedlund; Jann Hau; Carina Carlsson; Torgny Stigbrand; Uppsala universitet; []
    Nyckelord :Laboratory animals; Preadipocyte factor 1; delta like protein; Fetal antigen 1; Goto-Kakizaki; Zucker; adipokines; adipose tissue; diabetes; obesity; Försöksdjursvetenskap;

    Sammanfattning : The timing of cell differentiation is important for development and renewal of well functioning organs and tissues. One protein involved in this process is Preadipocyte factor 1 (Pref-1). Most likely, the role of this protein is to maintain cells in an undifferentiated state. LÄS MER

  4. 13. Recombinant antibodies and tumor targeting

    Författare :Ali Sheikholvaezin; Torgny Stigbrand; Gregory P Adams; Umeå universitet; []
    Nyckelord :immunologi; Immunology;

    Sammanfattning : Different antibody derived constructs are rapidly advancing as putative tools for treatment of malignant diseases. Antibody engineering has added significant new technologies to modify size, affinities, solubility, stability and biodistribution properties for immunoconjugates. LÄS MER

  5. 14. Vaccine Therapy of Colorectal Cancer Patients with Tumor Associated Antigens

    Författare :Gustav Ullenhag; Håkan Mellstedt; Carl Magnusson; Bengt Glimelius; Torgny Stigbrand; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Oncology; Colorectal cancer; GM-CSF; vaccination; CEA; ALVAC-KSA; IgG subclass; epitopes; Onkologi; Oncology; Onkologi; Oncology; onkologi;

    Sammanfattning : In this thesis, two different vaccines were evaluated as adjuvant therapy for patients with colorectal cancer. The ability of the two candidate vaccines to generate antigen-specific cellular and humoral responses, respectively, was studied. LÄS MER