Sökning: "Zucker"
Visar resultat 1 - 5 av 11 avhandlingar innehållade ordet Zucker.
1. A Possible World: Autism from Practice to Theory
Sammanfattning : Persons with autism develop along trajectories that differ from the typical. Therefore, development itself gives important clues for understanding the behavioral profile characteristic of autism. Developing autism means being different, not necessarily being deficient. LÄS MER
2. Protein and mRNA Studies of Rat FA1/Pref-1/dlk
Sammanfattning : The timing of cell differentiation is important for development and renewal of well functioning organs and tissues. One protein involved in this process is Preadipocyte factor 1 (Pref-1). Most likely, the role of this protein is to maintain cells in an undifferentiated state. LÄS MER
3. Structural and biochemical insights into biosynthesis and degradation of N-glycans
Sammanfattning : Carbohydrates are a primary energy source for all living organisms, but importantly, they also participate in a number of life-sustaining biological processes, e.g. cell signaling and cell-wall synthesis. The first part of the thesis examines glycosyltransferases that play a crucial role in the biosynthesis of N-glycans. LÄS MER
4. Optimizing nicotinic acid delivery for durable antilipolysis and improved metabolic control
Sammanfattning : Type 2 diabetes is a devastating disease affecting hundreds of millions worldwide. Lipid accumulation in peripheral non-adipose tissues is a major driver of insulin resistance, a central pathophysiological defect of this disease. LÄS MER
5. Mechanisms of insulin signaling and the role of caveolae
Sammanfattning : Insulin regulates metabolic as well as mitogenic processes in target cells, involving a large number of mediators of signal transduction. In its role as a growth factor, insulin stimulates cell growth, in a process we demonstrate requires the participation of the Raf-1 kinase. LÄS MER