Sökning: "SRA - Molecular Bioscience"

Visar resultat 16 - 20 av 21 avhandlingar innehållade orden SRA - Molecular Bioscience.

1. 16. Computational Modeling of Cancer Progression

   Författare :Hossein Shahrabi Farahani; Jens Lagergren; Niko Beerenwinkel; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cancer progression; Bayesian networks; microRNA editing; SRA - Molekylär biovetenskap; SRA - Molecular Bioscience;

   Sammanfattning : Cancer is a multi-stage process resulting from accumulation of genetic mutations. Data obtained from assaying a tumor only contains the set of mutations in the tumor and lacks information about their temporal order. Learning the chronological order of the genetic mutations is an important step towards understanding the disease. LÄS MER

3. 17. Advances in DNA Detection

   Författare :Yajing Song; Olof Emanuelsson; Jonas Tegenfeldt; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; DNA detection; active filter paper; visual detection; throughput; fluorescence; superparamagnetic beads; rare DNA; Q-PCR; chemical fragmentation; DNA library preparation; massively parallel sequencing; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

   Sammanfattning : DNA detection technologies have an increasing importance in our everyday lives, with applications ranging from microbial diagnostics to forensic analysis, food safety evaluation, and environmental monitoring. Currently, as the associated costs decrease, DNA diagnostic techniques are routinely used in research laboratories, in clinical and forensic practice. LÄS MER

4. 18. Advances in DNA Detection on Paper Chips

   Författare :Yajing Song; Olof Emanuelsson; Mats Nilsson; Aman Russom; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; DNA detection; active filter papers; visualization; throughput; fluorescence; superparamagnetic beads; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

   Sammanfattning : DNA detection has an increasing importance in our everyday lives, with applications ranging from microbial diagnostics to forensic analysis. Currently, as the associated costs decrease, DNA diagnostic techniques are routinely used not only in research laboratories, but also in clinical and forensic practice. LÄS MER

5. 19. Characterization of Antigenic Properties and High Throughput Protein Purification

   Författare :Johanna Steen; Sophia Hober; Mats Ohlin; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; high throughput; protein purification; sample preparation; antigen solubility; immunogenicity; epitope mapping; antigen design; Bioengineering; Bioteknik; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

   Sammanfattning : To understand the cellular processes, knowledge of the localization and function of proteins are essential. There are several high throughput ventures examining the human proteome. However, there are some bottlenecks in these ventures. For example the production and expression of soluble proteins for analysis. LÄS MER

7. 20. Exploring glycoside hydrolase family 5 (GH5) enzymes

   Författare :Yang Wang; Ines Ezcurra; Henrik Aspeborg; Henrik Stålbrand; Torkel Berglund; KTH; []
   Nyckelord :GH5; glycoside hydrolase; subfamily classification; mannans; polysaccharides; mannanases; cell wall; GH5; glykosidhydrolas; subfamiljklassificering; mannaner; polysackarider; mannanaser; cellvägg; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

   Sammanfattning : In 1990, the classification of carbohydrate-active enzymes (CAZymes) was introduced by the scientist Bernard Henrissat. According to sequence similarity, these enzymes were separated into families with conserved structures and reaction mechanisms. LÄS MER