Sökning: "Anti-D"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet Anti-D.

1. 1. Anti-D antibodies : In vitro tests to predict the severity of hemolytic disease of the newborn

   Författare :Jan-Olof Hildén; Lennart Rydberg; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : The ability of different in vitro tests to predict the severity of hemolytic disease of the newborn (HDN) has been studied. When properly performed the traditional indirect antiglobulin titers (IAT) on maternal serum can be used to identify a low !iter group ~32 in which the fetus will not suffer from severe hemolytic disease and a high titer group ~1000 where all newboms will be affected. LÄS MER

3. 2. Alloimmunization during pregnancy with special emphasis on anti-D : Laboratory and clinical management

   Författare :Derek Filbey; Lennart Rydberg; Linköpings universitet; []
   Nyckelord :Alloimmunization in pregnancy; Anti-D; Haemolytic disease of the newborn HDN ; IAT-titration; AA-quantitation; Chemiluminescence test; Category D; HLA class II antibodies; MEDICINE; MEDICIN;

   Sammanfattning : The laboratory and clinical management of alloimmunized in pregnancy has been investigated according to a protocol currently in use in Örebro region. A 12 year epidemiological study showed the prevalence of alloimmunization to be 0.57% in this Swedish populationwith a 0. LÄS MER

4. 3. Antibodies during pregnancy : Aspects on complications during pregnancy and complications related to transfusion

   Författare :Miodrag Palfi; Olof Sjöberg; Linköpings universitet; []
   Nyckelord :Pregnancy; Thl; Th2; hernolytic disease of the newborn; anti-D; IgG subclasses; IgG transport; post-transfusion reactions; acute lung injury; MEDICINE; MEDICIN;

   Sammanfattning : The fetus acquires half of its genetic infonnation from the father and represents a foreign graft in pregnancy. The overall mechanisms contributing to immunologic tolerance and successful pregancy still are an enigma. Accumulating results of immunologic research, however, offer an explanation for many events in pregnancy. LÄS MER

5. 4. New strategies to prevent fetal and neonatal complications in Rhesus D immunization

   Författare :Eleonor Tiblad; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The general purpose of this thesis was to investigate if fetal and neonatal complications due to RhD immunization in the mother could be prevented by 1) reducing procedure-related complications in intrauterine blood transfusions and by 2) reducing the incidence of RhD immunization by providing routine antenatal anti-D prophylaxis during pregnancy selectively to non-immunized RhD negative women with RhD positive fetuses. Paper I was a retrospective study including 284 intrauterine transfusions in 84 women 1990-2010. LÄS MER

7. 5. Red cell alloimmunization during pregnancy

   Författare :Tomas Gottvall; Magnus Westgren; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : We have evaluated a new screening program to detect red cell alloimmunization during pregnancy that was introduced in the south-east region of Sweden in 1981. The screening program is based on two antibody tests at 25 and 35 gestational weeks for all pregnant  women regardless of maternal Rh(D) status. LÄS MER