Sökning: "antigen solubility"

Hittade 4 avhandlingar innehållade orden antigen solubility.

  1. 1. Characterization of Antigenic Properties and High Throughput Protein Purification

    Författare :Johanna Steen; Sophia Hober; Mats Ohlin; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; high throughput; protein purification; sample preparation; antigen solubility; immunogenicity; epitope mapping; antigen design; Bioengineering; Bioteknik; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

    Sammanfattning : To understand the cellular processes, knowledge of the localization and function of proteins are essential. There are several high throughput ventures examining the human proteome. However, there are some bottlenecks in these ventures. For example the production and expression of soluble proteins for analysis. LÄS MER

  3. 2. Functional mapping and in vivo metabolism of the monoclonal antibody TS1 and its single-chain fragment : Its interaction with the antigen and the anti-idiotype

    Författare :Patrik Holm; Birgitta Sundström; Lars Gedda; Karlstads universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; single-chain antibody; functional mapping; site-directed mutagenesis; immune complex; metabolism; Molecular biology; Molekylärbiologi; Biomedical Laboratory Science; Biomedicinsk laboratorievetenskap;

    Sammanfattning : Antibodies are proteins capable of specific interactions to a wide range of molecules. These interactions are facilitated by the complementary determining regions (CDR).Carcinomas are the most common of human cancers and they release significant amount of cytokeratins (CK) in the necrotic areas of the tumors. LÄS MER

  4. 3. Exported proteins of the malaria parasite Plasmodium falciparum : characterization of blood-stage antigen 332

    Författare :Sandra Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Plasmodium falciparum malaria is one of the most important infectious diseases in the world. Following invasion of the human red blood cell (RBC), the P. LÄS MER

  5. 4. In vitro analyses of immune responses to metal and organic haptens in humans with contact allergy

    Författare :Khosro Masjedi; Marita Troye-Blomberg; Niklas Ahlborg; Lone Skov; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ELISpot; contact allergy; parthenolide; methylisothiazolinones; nickel; hapten; Allergology; Allergologi; immunologi; Immunology;

    Sammanfattning : Contact allergy is one of the most common skin diseases with great social and economical impact. The origin and nature of contact allergens (haptens) capable of inducing T-cell mediated allergic reactions are diverse, ranging from organic molecules to metal ions. LÄS MER