Sökning: "SOFIE"

Visar resultat 16 - 20 av 204 avhandlingar innehållade ordet SOFIE.

  1. 16. Nitric oxide and evaluation of different treatments in experimental colitis and inflammatory bowel disease

    Författare :Sofie Lundberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is a chronic inflammatory disorder of unknown etiology of the gastrointestinal tract. Central features of IBD are increased nitric oxide (NO) generation in the gut lumen and dysfunction in regulation of leukocyte recruitment from the blood stream towards the affected tissue. LÄS MER

  3. 17. IGF, PI3K and HIF-2 in Normal and Tumor Development

    Författare :Sofie Mohlin; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroblastoma; Hypoxia; Insulin-like Growth Factor; PI3K; HIF-2alpha; Cancer; Development;

    Sammanfattning : Cells adapt to oxygen shortage, hypoxia, by inducing a transcriptional shift governed mainly by Hypoxia Inducible Factor (HIF)-1 and HIF-2. In various cancer forms, including neuroblastoma, high expression of HIF-2α correlates with disseminated disease and poor outcome. LÄS MER

  4. 18. Systematics of polyploid Dactylorhiza (Orchidaceae) - genetic diversity, phylogeography and evolution

    Författare :Sofie Olofsson; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; microsatellites; allozymes; ITS; plastid DNA; Dactylorhiza majalis ssp. traunsteineri; allopolyploidy; AFLPs; immigration history; diploidization; hybridization;

    Sammanfattning : This thesis examines genetic variation in allotetraploids of the Dactylorhiza incarnata/maculata polyploid complex in different parts of Europe. The molecular markers used were AFLPs, allozymes, ITS, nuclear microsatellites and plastid DNA markers. LÄS MER

  5. 19. Socioeconomic Consequences of Childhood Onset Type 1 Diabetes – a case study of the impact of an early life health shock

    Författare :Sofie Persson; Hälsoekonomi; []
    Nyckelord :Type 1 diabetes; health; socioeconomic outcomes; education; employment; earnings;

    Sammanfattning : Type 1 diabetes is a lifelong, chronic disease, that generally has a sudden onset early in life, which changes the conditions for the affected child and the child’s family. The overall purpose of this thesis was to explore the socioeconomic consequences of childhood onset type 1 diabetes and through this investigate how an early life health shock can affect adult socioeconomic status. LÄS MER

  7. 20. Physical activity and quality of life in women treated with Roux-en-Y gastric bypass surgery : a randomized controlled trial and qualitative interviews

    Författare :Sofie Possmark; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Introduction: Bariatric surgery is the most effective method for weight loss and long-term weight loss maintenance, but requires several changes in health behaviors. In Sweden, Roux-en-Y Gastric Bypass (RYGB) is the most common bariatric surgery method, as it accounted for 49.3% of the bariatric procedures in 2018. LÄS MER