Sökning: "SOFIE"

Visar resultat 6 - 10 av 204 avhandlingar innehållade ordet SOFIE.

  1. 6. Small Cajal body-associated RNA 2 and RNA-binding protein WRAP53β in DNA repair and Hoyeraal-Hreidarsson syndrome

    Författare :Sofie Bergstrand; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The DNA in our cells can be damaged through many different mechanisms and correct repair of DNA lesions is of utmost importance to ensure genomic integrity and prevent alteration in the genetic code contributing to diseases such as cancer, neurodegenerative disorders and premature aging. Non-coding RNAs were for a long time considered as non-functional transcriptional byproducts. LÄS MER

  3. 7. Cell cycle regulatory proteins and miRNAs in premalignant lesions and breast cancer

    Författare :Sofie Björner; Malmö Patologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Early diagnosis and reliable prognosis and treatment prediction of breast cancer will ultimately lead to a decreased mortality rate. This can be achieved by identification of prognostic and treatment predictive biomarkers, and by understanding the mechanisms behind early changes in the breast. LÄS MER

  4. 8. Clinical encounters with different illness realities : qualitative studies of illness and restructuring of illness meaning among two cultural groups of female patients in a multicultural area of Stockholm

    Författare :Sofie Bäärnhielm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Transcultural psychiatry; somatization; illness meaning; immigration; sense of coherence;

    Sammanfattning : Background: Mental health care in Sweden encounters a multicultural population. Meaning given to illness may differ between patient, family and caregiver and this affects the clinical encounter and outcome of treatment. LÄS MER

  5. 9. 3D Verification of Dynamic and Breathing Adapted Radiotherapy using Polymer Gel Dosimetry

    Författare :Sofie Ceberg; Malmö Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiotherapy; 3D verification; polymer gel;

    Sammanfattning : Polymer gel dosimetry has been used since the 1990s, and several studies have shown that this detector system can be used for verification of static absorbed dose distributions in three dimensions (3D). Its unique properties, such as high resolution, normal tissue equivalence and independency of energy, field size and direction of the incident radiation, should also be advantageous for dosimetric verification of radiotherapy using today’s and tomorrow’s dynamic delivery techniques. LÄS MER

  7. 10. Essays on Human Capital Investments: Pharmaceuticals and Education

    Författare :Sofie Gustafsson; Nationalekonomiska institutionen; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Pharmaceutical utilization; Adherence; Human capital; Grossman model; Health; Education; Diabetes; Non-monotonic health investments; Steady-state and stable equilibria .;

    Sammanfattning : This thesis consists of four essays on individual health behaviour and investment in higher education. Three of them consider different aspects of pharmaceutical utilization and aim at explaining some of the observed individual variation in access and adherence to treatment regimens. LÄS MER