Sökning: "Restricted recombination"

Visar resultat 6 - 10 av 19 avhandlingar innehållade orden Restricted recombination.

  1. 6. Studies of Genome Diversity in Bartonella Populations : A journey through cats, mice, men and lice

    Författare :Hillevi Lina Lindroos; Siv G. E. Andersson; Richard Birtles; Uppsala universitet; []
    Nyckelord :Biology; Bartonella; genome content; genome rearrangement; gene expression; phage; microarray; PFGE; MLST; Biologi;

    Sammanfattning : Bacteria of the genus Bartonella inhabit the red blood cells of many mammals, including humans, and are transmitted by blood-sucking arthropod vectors. Different species of Bartonella are associated with different mammalian host species, to which they have adapted and normally do not cause any symptoms. LÄS MER

  3. 7. On the engineering of proteins: methods and applications for carbohydrate-active enzymes

    Författare :Fredrika Gullfot; Harry Brumer; Antoni Planas; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; enzyme engineering; rational design; directed evolution; DNA shuffling; glycosynthase; xyloglucan; xyloglucan endo-transglycosylase; retaining glycoside hydrolase; xyloglucanase; carbohydrate binding module; polysaccharide synthesis; Bioengineering; Bioteknik;

    Sammanfattning : This thesis presents the application of different protein engineering methods on enzymes and non-catalytic proteins that act upon xyloglucans. Xyloglucans are polysaccharides found as storage polymers in seeds and tubers, and as cross-linking glucans in the cell wall of plants. LÄS MER

  4. 8. Full circle : Rise and fate of genetic variation in Marasmius oreades fairy rings

    Författare :Markus Hiltunen; Hanna Johannesson; Martin Ryberg; Jason Stajich; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mushroom; fairy ring; Marasmius; mutation; fungi; genomics; Biology with specialization in Systematics; Biologi med inriktning mot systematik;

    Sammanfattning : Genetic variation is a prerequisite for evolution. The degree of variability within a species is governed by forces including mutation, recombination and selection. LÄS MER

  5. 9. Studies on Molecular Genetics of B cell Development

    Författare :Panagiotis Tsapogas; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunoglobulin; gene expression; B cell; EBF; class switching; TGF-beta; Immunology; transplantation; serologi; Immunologi; serology;

    Sammanfattning : The development of immature progenitor cells into highly differentiated effector cells is a process central in modern medicine with applications in the fields of cell therapy as well as oncology. This thesis is focused on the molecular mechanisms that control the development of B lymphocytes. LÄS MER

  7. 10. The Road to Maturity - Lineage Commitment in early Hematopoiesis

    Författare :Charlotta Böiers; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The road to maturity – how do hematopoietic stem cells (HSC) differentiate into mature blood cells? The pathways of lineage commitment during normal hematopoiesis are of great significance in order to understand the underlying events that lead to leukemia, and to the design of proper treatments for prevention and remission of the disease. The route of hematopoiesis can be thought of as a hierarchical tree, with the rare HSCs at the top, transitioning down along the pathways as different progenitors. LÄS MER