Sökning: "Restricted recombination"

Visar resultat 16 - 19 av 19 avhandlingar innehållade orden Restricted recombination.

  1. 16. Transcription factors regulating the immunoglobulin heavy chain locus

    Författare :Tove Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The immunoglobulin heavy (IgH) chain locus is subject to somatic recombination and changes in gene expression in B lineage cells. Enhancers located in the 3' end of the locus may in part regulate these events. This work aimed at increasing the understanding of the function of one of these elements, the HS1,2 enhancer. LÄS MER

  3. 17. Defining human adaptive immune gene diversity

    Författare :Sanjana Narang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The lymphocytes (B and T cells) of the adaptive immune system undergo variable (V), diversity (D), and junctional (J) gene recombination, resulting in highly diverse antigen receptor repertoires capable of recognizing a wide variety of invading pathogens. The B cell receptor (BCR) contains two identical heavy and light chains. LÄS MER

  4. 18. Welander distal myopathy : clinical and genetic studies

    Författare :Gabrielle Åhlberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Welander distal myopathy; neurogenic component; rimmed vacuoles; linkage; chromosome 2p13; candidate genes; common founder; homozygous form; variable clinical expression;

    Sammanfattning : Distal myopathies are a group of muscular disorders described in many countries with different inheritance patterns and variable progression rates. Welander distal myopathy (WDM) is characterised by autosomal dominant inheritance, late onset and distal distribution of muscular weakness. Most cases originate from the middle parts of Sweden. LÄS MER

  5. 19. Engineering Multicomponent Nanostructures for MOSFET, Photonic Detector and Hybrid Solar Cell Applications

    Författare :Asghar Jamshidi Zavaraki; Hans Ågren; Kevin J. Webb; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Epitaxial G rowth; Reduced Pressure Chemical Vapor Deposition; GeSnSiC; MOSFET; Photonic Detector; Resistivity; Phosp hor and Boron doping; Colloidal QDs Sensitized Solar Cell; Cd - free and Cd - based QDs; High Resolution Reciprocal Lattice Map; High Resolution X - Ray Diffraction; High Resolution Transmission Electron Microscopy; High resolution Scanning E lectron Microscopy .;

    Sammanfattning : Silicon technologyhas been seekingfor a monolithic solution for a chip where data processing and data communication is performed in the CMOS part and the photonic component, respectively. Traditionally, silicon has been widely considered for electronic applications but not for photonic applications due to its indirect bandgap nature. LÄS MER