Sökning: "Radioimmunotherapy"
Visar resultat 6 - 10 av 27 avhandlingar innehållade ordet Radioimmunotherapy.
6. Activity quantification based on scintillation camera imaging - Application to 111In/90Y radioimmunotherapy
Sammanfattning : Radionuclide therapy (RNT), is important for the treatment of certain benign and malignant diseases. 90Y-Zevalin™ therapy has become an established method of treating patients with non-Hodgkin B-cell lymphoma. LÄS MER
7. Alpha-radioimmunotherapy with At-211: Evaluations and imaging on normal tissues and tumors
Sammanfattning : Alpha-radioimmunotherapy (alpha-RIT) is an internal conformal radiotherapy at the cellular level using alpha-particle emitting radionuclides. Alpha-particles have a very short range in tissues (... LÄS MER
8. Astatine-211 and Iodine Conjugates: Radiohalogenation and Preclinical Pharmacokinetics for Targeted and Pretargeted Radioimmunotherapy
Sammanfattning : Endoradiotherapy using labelled tumour specific-monoclonal antibodies in the therapy of malignant disease is a therapeutic modality that is coming of age. While clearly defined tumours can be treated with surgery and/or chemotherapy, occult metastases requires adjuvant systemic treatment, e.g. LÄS MER
9. Radioimmunoimaging and Radioimmunotherapy of Prostate Cancer Preclinical evaluation of kallikrein related peptidase 2 targeting
Sammanfattning : Prostate cancer is one of the major causes of cancer related deaths in men in Europe and the United States. In this doctoral thesis, radioimmunoimaging and -therapy of prostate cancer was investigated pre-clinically by targeting the human kallikrein-related peptidase 2 (hK2) with radiolabelled monoclonal antibodies. LÄS MER
10. Astatine-211 radioimmunotherapy of ovarian cancer. Therapeutic efficacy, myelotoxicity, andradiation dosimetry in an animal model
Sammanfattning : Alpha-particle emitting radionuclides have recently obtained an increased attention whenconsidering new strategies for treating disseminated cancer. Astatine (211At), that emits alphaparticleswith a mean path length of 62 μm, a mean linear energy transfer (LET) of 111keV/Mum, and a half-life of 7. LÄS MER