Sökning: "radioimmunotherapy"

Visar resultat 1 - 5 av 26 avhandlingar innehållade ordet radioimmunotherapy.

  1. 1. Experimental radioimmunotherapy and effector mechanisms

    Detta är en avhandling från Umeå : Klinisk mikrobiologi

    Författare :David Eriksson; Umeå universitet.; Umeå universitet.; Umeå universitet.; [2006]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; radioimmunotherapy; apoptosis; mitotic catastrophe; caspases; cell cycle disturbances; combination treatment.; NATURAL SCIENCES Biology Cell and molecular biology Immunology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Immunologi;

    Sammanfattning : Radioimmunotherapy is becoming important as a new therapeutic strategy for treatment of tumour diseases. Lately monoclonal antibodies tagged with radionuclides have demonstrated encouraging results in treatment of hematological malignancies. The progress in treatment of solid tumours using radioimmunotherapy, however, has been slow. LÄS MER

  2. 2. Optimizing experimental radioimmunotherapy investigating the different mechanisms behind radiation induced cell deaths

    Detta är en avhandling från Umeå : Umeå Universitet

    Författare :Theres Lindgren; Umeå universitet.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mitotic catastrophe; senescence; cell cycle checkpoint; apoptosis; radiation; gene expression; p53; immunologi; Immunology; radiofysik; radiofysik;

    Sammanfattning : Background. Radiation therapy is an important treatment regimen for malignant disease. Radiation therapy uses ionizing radiation to induce DNA damage in tumor cells in order to kill them. LÄS MER

  3. 3. Pharmacokinetics and dosimetry in intraperitoneal radioimmunotherapy with 211At

    Detta är en avhandling från Göteborg : University of Gothenburg

    Författare :Elin Cederkrantz; Göteborgs universitet.; Gothenburg University.; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; astatine-211; radioimmunotherapy; alpha-emitter; ovarian cancer; MX35; pharmacokinetics; dosimetry; effective dose;

    Sammanfattning : The prognosis for patients diagnosed with disseminated cancer is often poor. Radioimmunotherapy (RIT) is a new approach to treat disseminated disease. The aim is to target tumor cells with monoclonal antibodies (mAbs) labeled with radionuclides which release cytotoxic particle radiation upon decay. The radionuclide 211At, with half-life 7. LÄS MER

  4. 4. Radioimmunotherapy in Experimental Head and Neck Squamous Cell Carcinoma Tumour-targeting in vitro and in vivo

    Detta är en avhandling från Göteborg : University of Gothenburg

    Författare :Junping Cheng; Uppsala universitet.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Otorhinolaryngology; squamous cell carcinoma; radioimmunotherapy; cell line; tumour targeting; radionuclide; nude mice; Otorhinolaryngologi; MEDICINE Surgery Otorhinolaryngology; MEDICIN Kirurgi Otorhinolaryngologi;

    Sammanfattning : Radioimmunotherapy (RIT) has been shown to be a practicable way to treat head and neck squamous cell carcinoma. A specific antibody recognizes the charasteristic structure of tumour cells when loaded with cytotoxic agents (toxins, drugs, radionuclides, etc). LÄS MER

  5. 5. Development of targeted alpha therapy with Bi-213 and At-211 for the treatment of disseminated cancer

    Detta är en avhandling från Göteborg : University of Gothenburg

    Författare :Anna Gustafsson; Göteborgs universitet.; Gothenburg University.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alpha particles; astatine; bismuth; MX35; ovarian cancer; polylysine; pretargeted radioimmunotherapy; radioimmunotherapy;

    Sammanfattning : Radioimmunotherapy (RIT) is a type of targeted cancer therapy. The concept behind RIT is to deliver cytotoxic ionizing radiation to tumor cells by attaching radionuclides to tumor-specific antibodies. LÄS MER