Sökning: "Pseudomonas aeruginosa infection"

Visar resultat 21 - 25 av 33 avhandlingar innehållade orden Pseudomonas aeruginosa infection.

  1. 21. Regulation of bacterial adaptive behavior by the second messenger cyclic-di-GMP and host components

    Författare :Soazig Le Guyon; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : To optimize survival and growth, bacteria have evolved adaptive behaviors that respond to relevant environmental signals. A switch from the motile to the sessile lifestyle is probably the most ancient behavioral transition of microorganisms. LÄS MER

  3. 22. Studies on Staphylococcus epidermidis biofilm formation and the bacterial interaction with the human cathelicidin antimicrobial peptide LL-37

    Författare :Eva Hell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The long-term use of central venous catheters for delivering nutrients and drugs in preterm neonates has been related to nosocomial infections. The majority of late-onset sepsis in very preterm infants (... LÄS MER

  4. 23. Respiratory Tract Infections: Aspects of Aetiology, Virulence, and Communicable Disease Control

    Författare :Jonas Ahl; Enheten för infektionssjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Streptococcus pneumoniae; day care center; communicable disease control intervention; eradication therapy; invasive pneumococcal disease; serotype 3; aetiology; ventilator-associated pneumonia;

    Sammanfattning : The paediatric nasopharyngeal flora is regarded as the largest reservoir for Streptococcus pneumoniae, and the carrier state is always antecedent to infection and a prerequisite for dispersion of these bacteria. Pneumococci are the predominant aetiology of bacterial respiratory tract infections and a major cause of morbidity and mortality, in the most severe cases due to invasive pneumococcal disease (IPD; mainly sepsis and meningitis). LÄS MER

  5. 24. Chemical attenuation of bacterial virulence : small molecule inhibitors of type III secretion

    Författare :Anna Kauppi; Mikael Elofsson; Anders Karlén; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; antibiotic resistance; virulence; type III secretion; T3SS inhibitors; Yop; SMD; QSAR; screening; Yersinia pseudotuberculosis; Organic chemistry; Organisk kemi;

    Sammanfattning : Despite the large arsenal of antibiotics available on the market, treatment of bacterial infections becomes more challenging in view of the fact that microbes develop resistance against existing drugs. There is an obvious need for novel drugs acting on both old and new targets in bacteria. LÄS MER

  7. 25. Quantifying effects of antimicrobial drug combinations by modelling and simulation

    Författare :Chenyan Zhao; Lena Friberg; Elisabet I. Nielsen; Shampa Das; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacokinetics and pharmacodynamics; modelling and simulation; antibiotic combination; model-based translation; antibiotic resistance; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Antibiotic resistance is becoming an accelerating issue, both in the treatment of nosocomial infections and for public health in general. There is a pressing need for innovative methods to understand how available antibiotics could be combined to overcome and limit the emergence of resistance. LÄS MER