Sökning: "Pneumococcal conjugate vaccines"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden Pneumococcal conjugate vaccines.

1. 1. Invasive Pneumococcal Infections

   Författare :Erik Backhaus; Göteborgs universitet; []
   Nyckelord :Streptococcus pneumoniae; epidemiology; risk factors; pneumonia; meningitis; serotype; clonal complex;

   Sammanfattning : Streptococcus pneumoniae is a major cause of disease, ranging from uncomplicated respiratory infections to severe invasive pneumococcal disease (IPD), including bacteraemic pneumonia, septicaemia with unknown focus and meningitis. Case fatality rate (CFR) remains high and antibiotic resistance is increasing globally. S. LÄS MER

3. 2. Impact of the inflammatory response on specific immunity in neurosurgical patients

   Författare :Anna Ljunghill Hedberg; Jan Sjölin; Karlis Pauksen; Lars Hagberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; T-cell-dependent vaccine; T-cell-independent vaccine; CNS injury-induced immune deficiency syndrome; pneumococcal conjugate vaccine; pneumococcal polysaccharide vaccine; posttraumatic meningitis.; Medicinsk vetenskap; Medical Science; Infektionssjukdomar; Infectious Diseases;

   Sammanfattning : Vaccination with a T-cell-dependent pneumococcal conjugate vaccine (PCV) followed by a T-cell-independent pneumococcal polysaccharide vaccine (PPSV) is recommended after basilar skull fracture to reduce the risk of meningitis. The optimal time frame for vaccination has not yet been established and varies widely in practice. LÄS MER

4. 3. Antibiotic use and respiratory pathogens with focus on Streptococcus pneumoniae in Tanzanian children

   Författare :Matilda Emgård; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antimicrobial stewardship; Drug resistance; Bacterial; Drug prescribing; Infant; Pneumococcal conjugate vaccines; Streptococcus pneumoniae; Tanzania; Viruses;

   Sammanfattning : This thesis describes the epidemiology of Streptococcus pneumoniae (pneumococci) and other respiratory pathogens after introduction of the 13-valent pneumococcal conjugate vaccine (PCV13) and further portrays antibiotic use in Tanzanian children. Pneumococci are a leading cause of pneumonia in children. LÄS MER

5. 4. Impact of pneumococcal conjugate vaccine on pneumococcal disease, carriage and serotype distribution : comparative studies in Sweden and Uganda

   Författare :Ann Lindstrand; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Background: Streptococcus pneumoniae is a leading infectious cause of child deaths worldwide. Pneumococcal conjugate vaccine (PCV) was first introduced in the US in the year 2000, and included the major seven pneumococcal serotypes (PCV7) causing invasive pneumococcal disease (IPD) there. LÄS MER

7. 5. Infectious and bleeding complications in patients with hematological malignancies : Studies on diagnosis and prevention

   Författare :Tobias Svensson; Honar Cherif; Martin Höglund; Jan Sjölin; Christine Wennerås; Uppsala universitet; []
   Nyckelord :Chronic lymphocytic leukemia; Immunodeficiency; Hypogammaglobulinemia; IgG subclass; Pneumococci; Pneumococcal vaccine; Polysaccharide vaccine; Protein-conjugate vaccine; Aspergillosis; Bronchoalveolar lavage; Invasive fungal disease; Pneumocystis jirovecii pneumonia; Myelodysplastic syndrome; Azacitidine; Eltrombopag; Thrombocytopenia; Thrombopoietin receptor; Oncology; Onkologi;

   Sammanfattning : The overall aim of this thesis is to improve knowledge about the prevention of infectious and bleeding complications in patients with hematological malignancies, primarily in those with chronic lymphocytic leukemia (CLL) and myelodysplatic syndrome (MDS).Hypogammaglobulinemia, impaired production of immunoglobulins (Ig), is an established risk factor for infection, but the impact of IgG pure subclass deficiency (IgG subclass deficiency with adequate production of IgG, IgA, and IgM) has been debated. LÄS MER