Sökning: "Hypogammaglobulinemia"

Hittade 3 avhandlingar innehållade ordet Hypogammaglobulinemia.

  1. 1. Infectious and bleeding complications in patients with hematological malignancies : Studies on diagnosis and prevention

    Författare :Tobias Svensson; Honar Cherif; Martin Höglund; Jan Sjölin; Christine Wennerås; Uppsala universitet; []
    Nyckelord :Chronic lymphocytic leukemia; Immunodeficiency; Hypogammaglobulinemia; IgG subclass; Pneumococci; Pneumococcal vaccine; Polysaccharide vaccine; Protein-conjugate vaccine; Aspergillosis; Bronchoalveolar lavage; Invasive fungal disease; Pneumocystis jirovecii pneumonia; Myelodysplastic syndrome; Azacitidine; Eltrombopag; Thrombocytopenia; Thrombopoietin receptor; Oncology; Onkologi;

    Sammanfattning : The overall aim of this thesis is to improve knowledge about the prevention of infectious and bleeding complications in patients with hematological malignancies, primarily in those with chronic lymphocytic leukemia (CLL) and myelodysplatic syndrome (MDS).Hypogammaglobulinemia, impaired production of immunoglobulins (Ig), is an established risk factor for infection, but the impact of IgG pure subclass deficiency (IgG subclass deficiency with adequate production of IgG, IgA, and IgM) has been debated. LÄS MER

  3. 2. Novel genetic associations with common variable immunodeficiency

    Författare :Omar Khalid Sharif Alkhairy; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Common variable immunodeficiency (CVID) is the most frequently encountered primary immunodeficiency disorder in clinical practice and is a cause of significant morbidity and mortality for patients. The main clinical features are hypogammaglobulinemia, recurrent infections and autoimmune disorders. LÄS MER

  4. 3. Genetic, cellular and clinical studies of hemophagocytic lymphohistiocytosis

    Författare :Marie Meeths; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hemophagocytic lymphohistocytosis (HLH) is a life-threatening hyperinflammatory condition characterized by fever, cytopenia, hepatosplenomegaly, and sometimes hemophagocytosis. HLH is typically divided into two distinct groups, primary HLH and secondary HLH. LÄS MER