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Visar resultat 1 - 5 av 30 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Roux-en-Y gastric bypass - clinical outcome and mechanisms of action

    Författare :Malin Werling; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Roux-en-Y gastric bypass; Obesity; Bariatric surgery; Energy chamber; Gastrointestinal hormones; GLP-1; PYY; Ghrelin; Energy expenditure; Body composition; Vertical Banded Gastroplasty; Indirect calorimetry; Overweight treatment; Weight loss;

    Sammanfattning : Roux-en-Y gastric bypass (gastric bypass) is an effective surgical technique for treating morbid obesity. The objective of this thesis is to increase knowledge of long-term outcomes of gastric bypass surgery and to elucidate some of the associated mechanisms of action. LÄS MER

  3. 2. Gastrointestinal Physiology and Results following Bariatric Surgery

    Författare :Jakob Hedberg; Magnus Sundbom; Näslund Erik; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bariatric surgery; gastric bypass; biliopancreatic diversion with duodenal switch; PYY; stomal ulcer; gastric emptying; Surgery; Kirurgi; Kirurgi; Surgery;

    Sammanfattning : The number of operations for morbid obesity is rising fast. We have examined aspects of postoperative physiology and results after bariatric surgery. The pH in the proximal pouch after Roux-en-Y gastric bypass (RYGBP) was investigated with catheter-based and wire-less technique. LÄS MER

  4. 3. Studies of the Neuropeptide Y Receptor Y2 in Human and Zebrafish

    Författare :Helena Fällmar; Dan Larhammar; Ingrid Lundell; Nina Mohell; Raquel E. Rodríguez Rodríguez; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Y2-receptor; NPY; PYY; G-protein-coupled receptor; mutagenesis; receptor binding; zebrafish; evolution; Pharmacology; Farmakologi; Farmakologi; Pharmacology;

    Sammanfattning : The G-protein coupled receptors (GPCRs) comprise the largest family of receptors in humans and other vertebrates. They are embedded in the cell membrane and are activated by many different signaling molecules. Activation modulates cellular signal transduction pathways and influences many physiological processes. LÄS MER

  5. 4. Gut Feelings - From Brain to Gut and from Lumen to Gut

    Författare :Xiaowen Cheng; Neurogastroenterologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Enteric nervous system; cerebral ischemia; galectine-3; tuft cell; CGRP; CCK; GLP-1; 5HT; PYY;

    Sammanfattning : Part 1: From Brain to GutThe brain is an organ with a high energy requirement. To meet this demand, the brain needs a continuous and well-regulated blood supply. In situations where the brain, or parts of the brain, does not receive sufficient blood flow injury arise. LÄS MER

  7. 5. Low Protein Diets and Their Effects on Brown Adipose Tissue

    Författare :Erik Lindsund; Jan Nedergaard; Eva Blomstrand; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Obesity; Protein diets; Dietary protein; Brown adipose tissue; Brown fat; BAT; UCP10; Uncoupeling protein 1; molekylär biovetenskap; Molecular Bioscience; fysiologi; Physiology;

    Sammanfattning : Obesity is a rising health issue and has been linked with a relative decrease of dietary protein, which promotes higher food intake. Brown adipose tissue is a heat-producing, energy-wasting organ that has been shown to be enhanced by a low protein diet. However, the mechanism of how this occurs is largely unknown. LÄS MER