Sökning: "PI 4 P"

Visar resultat 11 - 15 av 24 avhandlingar innehållade orden PI 4 P.

1. 11. Studies of the molecular genetics and epidemiology of porcine rubulavirus infection

   Författare :Julieta Sandra Cuevas Romero; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
   Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

   Sammanfattning : Porcine rubulavirus (PorPV) infection emerged spontaneously in pigs in Mexico in the early 1980s. Since the report of the initial outbreak of the disease, only one full-length genome from a strain isolated in 1984 (PorPV-LPMV/1984) has been sequenced. There is therefore limited information about the genetic variation of this virus. LÄS MER

3. 12. Characterization of parameters influencing intracellular bioavailability and prediction of intracellular drug exposure

   Författare :Andrea Treyer; Per Artursson; Gert Fricker; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intracellular drug bioavailability; unbound drug concentration; drug disposition; ADME; drug transport; drug metabolism membrane partitioning; phospholipid; drug-drug interaction; antisense oligonucleotide; cell-penetrating peptide; Farmaceutisk vetenskap; Pharmaceutical Science;

   Sammanfattning : This thesis work investigates factors influencing intracellular drug disposition. An experimental method for measurement of intracellular bioavailability (Fic), was used throughout. Fic is defined as the ratio between the unbound drug concentration inside the cell and the compound concentration in the cell exterior. LÄS MER

4. 13. Studies on proteins involved in the molecular regulation of insulin exocytosis

   Författare :Wei Zhang; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Actin; ADP; ATP; Ca2 channel; CAPS; beta-cells; CSP; exocytosis; GK rat; insulin; islet; Mint; Munc-18; NSF; PI 4-kinase; PI 4 P; PI 4; 5 P2; alpha-SNAP; SNAP-25; synaptotagmin III; syntaxin; tomosyn; type 2 diabetes mellitus; VAMP-2.;

   Sammanfattning : Type 2 diabetes mellitus is a disease characterized by impaired insulin secretion and insulin resistance. Better understanding of molecular mechanisms of insulin secretion may help to optimize type 2 diabetes management. LÄS MER

5. 14. En jämtländsk företagarverksamhet och dess omvärld : Sven O Perssons företagande 1920-1990

   Författare :Bo Boden; Umeå universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; structural change; business history; entrepreneurship; regional development; Jämtland; Sven O Persson; regional support policies; chipboard manufacturing; breweries; motor vehicles; Business and economics;

   Sammanfattning : The subject of this study is the business activities of an industrialist from county of Jämtland, Sven O Persson (S P), from the end of the 1910's to the end of the 1980's. The economic development of Jämtland during the last one hundred years has also been depicted and placed in relation to the national one, during periods of directional change and/or expansion. LÄS MER

7. 15. Phosphorus to horses and cows

   Författare :Gunilla Ögren; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
   Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

   Sammanfattning : It is important from a nutritional perspective to meet the phosphorus (P) requirements of animals. From an environmental perspective however, it is important not to feed more P than necessary, because excessive P will mainly be excreted with feces, and the soluble P fraction is vulnerable to runoff losses and may contribute to eutrophication. LÄS MER